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ANTI-FGFR2 ANTIBODIES IN COMBINATION WITH CHEMOTHERAPY AGENTS IN CANCER TREATMENT

Application US20260085123A1 Kind: A1 Mar 26, 2026

Assignee

FIVE PRIME THERAPEUTICS, INC.

Inventors

Helen L. COLLINS, James HNATYSZYN, Hong XIANG, Xiang ZHANG

Abstract

This application relates to uses of antibodies against fibroblast growth factor receptor 2 (FGFR2), including antibodies against the FGFR2 isoform FGFR2-IIIb (also known as FGFR2b), in treatment of certain cancers in combinations with mFOLFOX6 chemotherapy.

CPC Classifications

C07K 16/2863 A61K 9/0019 A61K 31/282 A61K 31/513 A61K 31/519 A61K 39/00 A61K 39/3955 A61P 35/00 A61P 35/04 A61K 2039/505 A61K 2039/545 C07K 2317/41 C07K 2317/732 C07K 2317/74 C07K 2317/76 C07K 2317/92

Filing Date

2025-05-05

Application No.

19199126