Nucleic Acid Storage and Transport at Ambient Temperatures
Summary
Board of Regents, The University of Texas System, published patent application US20260108624A1 (filed September 25, 2023) for liquid and substantially solid film compositions enabling long-term storage, transport, and delivery of nucleic acids and other molecules without ultralow temperature requirements. Inventors Trang Doan and Maria Croyle claim compositions that maintain nucleic acid integrity at ambient temperatures, potentially eliminating cold-chain storage needs for biological materials.
“Aspects of the present disclosure are directed to liquid and substantially solid film compositions for storage, transport, and administration of agents, including nucleic acids, without the use of ultralow temperatures.”
About this source
USPTO classification A61K covers pharmaceutical preparations: formulations, dosage forms, combination therapies, delivery systems, and the vehicles that carry active ingredients. Every newly published application in A61K lands in this feed, around 245 a month. Applications publish 18 months after filing, so this feed reveals what pharma formulators at major sponsors and generics were working on in the prior year and a half. Watch this if you compete in drug formulation, file freedom-to-operate analyses, scout competitive drug products before clinical readouts, or follow novel delivery platforms like nanoparticles, lipid carriers, and long-acting injectables.
What changed
The USPTO published patent application US20260108624A1 for The University of Texas System, disclosing compositions and methods for storing, transporting, and delivering nucleic acids and other therapeutic molecules at ambient temperatures without ultralow freezing. The application covers both liquid and substantially solid film formulations, and injectable or oral compositions comprising the disclosed nucleic acid formulations. No regulatory obligations are imposed by this publication.
Entities in the pharmaceutical, biotechnology, and research sectors should monitor this patent landscape for potential licensing opportunities or freedom-to-operate considerations. The disclosed compositions may compete with existing cold-chain dependent nucleic acid delivery systems, including certain mRNA vaccine and gene therapy platforms requiring frozen storage.
Archived snapshot
Apr 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
METHODS AND COMPOSITIONS FOR TRANSPORT, STORAGE, AND DELIVERY OF NUCLEIC ACIDS AND OTHER MOLECULES
Application US20260108624A1 Kind: A1 Apr 23, 2026
Assignee
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Inventors
Trang DOAN, Maria CROYLE
Abstract
Aspects of the present disclosure are directed to liquid and substantially solid film compositions for storage, transport, and administration of agents, including nucleic acids, without the use of ultralow temperatures. Provided are compositions capable of long-term storage of nucleic acids at ambient temperatures. Also disclosed are injectable or oral compositions comprising nucleic acids, as well as methods for formulation and administration of such compositions.
CPC Classifications
A61K 48/0041 A61K 47/16 A61K 47/22 A61K 47/26 A61K 47/32 C12Q 1/6806
Filing Date
2023-09-25
Application No.
19116798
Mentioned entities
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