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Navlimetostat Wet vs Dry Granulation Tablet PK Study

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Summary

A new Phase 1 clinical trial (NCT07544628) has been registered on ClinicalTrials.gov to compare the pharmacokinetics of Navlimetostat administered as a wet-granulation tablet versus a dry-granulation tablet formulation in healthy adult female participants. The study, registered by NIH, documents an early-stage bioequivalence investigation of two tablet manufacturing approaches for the drug candidate.

“This study aims to compare the PK of Navlimetostat after administration of a wet-granulation tablet versus the dry-granulation tablet formulation in healthy adult female”

NIH , verbatim from source
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About this source

ClinicalTrials.gov is the NIH-run registry of every clinical trial conducted in the United States, plus most international trials sponsored by US-based companies or institutions. By federal law, sponsors must register Phase 2 through Phase 4 studies before enrolling patients and post results within a year of completion. This feed tracks every new trial registration and study update, around 700 a month: drug interventions, device studies, behavioral protocols, observational research. Watch this if you scout drug candidates moving into mid or late-stage development, monitor competitor pipelines, or follow rare disease research where new trials signal patient hope. GovPing parses sponsor, phase, intervention, and target indication on each entry.

What changed

A Phase 1 clinical trial (NCT07544628) has been registered on ClinicalTrials.gov evaluating the pharmacokinetics of Navlimetostat administered as a wet-granulation tablet versus a dry-granulation tablet formulation. The study enrolls healthy adult female participants and is registered with an April 22, 2026 effective date.\n\nThis registry entry is informational and creates no regulatory obligations. Sponsors and clinical investigators monitoring competitive or同类药物 development may use this entry to track early-phase bioequivalence studies for Navlimetostat.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

A Phase 1 Study of Navlimetostat Tablet Formulations

Phase 1 NCT07544628 Kind: PHASE1 Apr 22, 2026

Abstract

This study aims to compare the PK of Navlimetostat after administration of a wet-granulation tablet versus the dry-granulation tablet formulation in healthy adult female

Conditions: Healthy Participants

Interventions: Navlimetostat

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Last updated

Classification

Agency
NIH
Published
April 22nd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Clinical investigators
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Clinical trial registration PK study Tablet formulation comparison
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Clinical Operations
Topics
Clinical Operations Healthcare

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