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Licaminlimab Phase 2 Dry Eye Disease Study

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Summary

A Phase 2 clinical trial (NCT07548632) evaluating the efficacy and safety of topical ophthalmic licaminlimab versus vehicle in participants with Dry Eye Disease and a specific genotype has been registered on ClinicalTrials.gov. The study includes an Artificial Tear Run-in period and will test licaminlimab against a vehicle placebo. The trial is categorized as Phase 2 and was posted on April 23, 2026.

“The primary objective of this study is to evaluate the efficacy and safety of the topical ophthalmic administration of licaminlimab as compared to vehicle in participants with Dry Eye Disease and a specific genotype.”

NIH , verbatim from source
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About this source

ClinicalTrials.gov is the NIH-run registry of every clinical trial conducted in the United States, plus most international trials sponsored by US-based companies or institutions. By federal law, sponsors must register Phase 2 through Phase 4 studies before enrolling patients and post results within a year of completion. This feed tracks every new trial registration and study update, around 700 a month: drug interventions, device studies, behavioral protocols, observational research. Watch this if you scout drug candidates moving into mid or late-stage development, monitor competitor pipelines, or follow rare disease research where new trials signal patient hope. GovPing parses sponsor, phase, intervention, and target indication on each entry.

What changed

A new Phase 2 clinical trial has been registered on ClinicalTrials.gov under NCT07548632, studying licaminlimab administered topically ophthalmically for Dry Eye Disease. The trial will compare licaminlimab against a vehicle placebo in participants with a specific genotype, with an Artificial Tear Run-in period included in the study design.

Pharmaceutical sponsors and clinical research organizations conducting ophthalmic drug trials should note this Phase 2 registration as it represents an active clinical development program for licaminlimab in an ocular indication. Study outcomes may inform future regulatory submissions for this candidate.

Archived snapshot

Apr 24, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

Phase 2 NCT07548632 Kind: PHASE2 Apr 23, 2026

Abstract

The primary objective of this study is to evaluate the efficacy and safety of the topical ophthalmic administration of licaminlimab as compared to vehicle in participants with Dry Eye Disease and a specific genotype.

Conditions: Dry Eye Disease (DED)

Interventions: Artificial Tear Run-in, licaminlimab, Vehicle of licaminlimab

View original document →

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Last updated

Classification

Agency
NIH
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Docket
NCT07548632

Who this affects

Applies to
Pharmaceutical companies Clinical investigators
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Clinical trial registration Drug efficacy study Ophthalmic research
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Clinical Operations
Topics
Healthcare Medical Devices

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