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MOCHA Perinatal Mental Health Integration Study Registration

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Summary

NIH registered observational study NCT07540585 examining a Collaborative Mental Health Care Program integrated into high-risk obstetric inpatient settings. The single-arm implementation study will assess feasibility, acceptability, and fidelity of delivering brief inpatient psychotherapy, symptom monitoring, and three-month post-discharge follow-up for pregnant and postpartum patients with depression, anxiety, ADHD, and PTSD symptoms.

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What changed

NIH registered a new observational study on ClinicalTrials.gov examining mental health care integration for high-risk perinatal patients. Project MOCHA tests a Collaborative Mental Health Care Program delivering brief inpatient psychotherapy and structured post-discharge follow-up over three months. The single-arm implementation study assesses feasibility, acceptability, and fidelity of the model. Preliminary outcomes in depression, anxiety, ADHD, and PTSD symptoms will inform future effectiveness trials and broader health system integration.

Healthcare providers and health system administrators involved in obstetric care may wish to monitor study outcomes, as positive findings could support business-case or quality-improvement arguments for embedding mental health services in maternity wards. The study's focus on trauma-informed approaches and structured follow-up protocols may also inform peer institutions developing similar integration programs.

Archived snapshot

Apr 20, 2026

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MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients

Observational NCT07540585 Kind: OBSERVATIONAL Apr 20, 2026

Abstract

Pregnant and postpartum patients hospitalized for medical complications experience high rates of depression, anxiety, and trauma-related symptoms, yet access to timely psychiatric care during obstetric hospitalization is limited. Project MOCHA integrates early mental health screening, trauma-informed psychotherapy, and structured follow-up into routine inpatient maternity care for individuals at elevated clinical risk.

This single-arm implementation study examines the feasibility, acceptability, and fidelity of delivering a Collaborative Mental Health Care Program within a high-risk obstetric inpatient setting. The program includes brief inpatient psychotherapy, symptom monitoring, and post-discharge follow-up over three months. Preliminary changes in depression, anxiety, attention-deficit hyperactivity disorder, and posttraumatic stress symptoms will be assessed to inform future effectiveness trials and broader health system integration.

Conditions: Anxiety Disorders, Stress Disorders, Post-Traumatic, Pregnancy, High Risk, Depressive Disorder, Major, Pregnancy Complications, ADHD - Attention Deficit Disorder With Hyperactivity

Interventions: Collaborative Mental Health Care Program (CMHCP)

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Last updated

Classification

Agency
NIH
Published
April 20th, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07540585

Who this affects

Applies to
Healthcare providers
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Mental health screening Inpatient psychiatric care
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Mental Health Public Health

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