Method for Detecting Polynucleotide Analyte Using CRISPR/Cas Effector
Summary
The USPTO has published a new patent application detailing a method for detecting polynucleotide analytes using CRISPR/Cas effector technology. The application, filed by inventors from USPTO, describes a method involving a cleaving agent with flap endonuclease activity and a type V CRISPR/Cas effector protein, specifically a Cast2 protein.
What changed
This document is a publication of a new US patent application (US20260085344A1) from the USPTO, titled 'Method for detecting polynucleotide analyte using CRISPR/Cas effector'. The application describes a novel method for detecting polynucleotide analytes in a sample, utilizing a cleaving agent with flap endonuclease activity in conjunction with a type V CRISPR/Cas effector protein, such as Cast2. The filing date was April 14, 2023.
While this is a patent application and not a regulation with direct compliance obligations, it signifies potential future technological advancements in nucleic acid detection. Companies in the biotechnology and pharmaceutical sectors involved in diagnostics or genetic analysis should monitor such patent filings as they may indicate emerging technologies that could impact future product development, intellectual property landscapes, or diagnostic methodologies. No immediate actions or deadlines are imposed by this publication.
Archived snapshot
Mar 27, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
METHOD OF DETECTING A POLYNUCLEOTIDE ANALYTE
Application US20260085344A1 Kind: A1 Mar 26, 2026
Inventors
Matthew Wook Chang, Nikhil Aggarwal, In Young Hwang, Hua Ling, Jee Loon Foo
Abstract
The invention relates generally to the field of nucleic acid detection. In particular, the specification teaches a method of detecting a polynucleotide analyte in a sample. In one aspect, the method comprises the use of a cleaving agent with flap endonuclease activity and a type V CRISPR/Cas effector protein. In another aspect, the type V CRISPR/Cas effector protein is a Cast 2 protein.
CPC Classifications
C12Q 1/6823 C12N 9/226 C12N 15/113 C12Q 1/25 C12Q 1/34 C12Q 1/48 C12Q 1/6844 C12Q 1/6876 C12Y 207/07007 C12Y 600/00 C12N 2310/20 C12Q 2600/156
Filing Date
2023-04-14
Application No.
18856243
Named provisions
Related changes
Get daily alerts for USPTO Patent Applications - Biotech (C12N)
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from USPTO.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when USPTO Patent Applications - Biotech (C12N) publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.