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MBSR Combined With Aerobic Training for Post-PCI Recovery

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Summary

A randomized controlled trial (NCT07544459) registered on ClinicalTrials.gov will evaluate mindfulness-based stress reduction (MBSR) combined with aerobic training versus aerobic training alone in 150 post-PCI coronary heart disease patients. The dual-intervention approach targets treatment adherence, kinesiophobia, heart rate variability, exercise tolerance, and psychological stress responses, with assessments using standardized scales including the TSK-SV Heart, SAS, and SDS. Results will inform cardiac rehabilitation practice, though no compliance obligations arise from this trial registration alone.

“Post-PCI patients (n = 150) were randomly assigned to an observation group (receiving combined MBSR and aerobic training) and a control group (receiving aerobic training only).”

NIH , verbatim from source
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About this source

GovPing monitors ClinicalTrials.gov Studies for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 725 changes logged to date.

What changed

This ClinicalTrials.gov registration documents a new randomized controlled trial evaluating MBSR combined with aerobic training in post-percutaneous coronary intervention cardiac rehabilitation. The study plans to enroll 150 patients, randomizing them to combined MBSR plus aerobic training or aerobic training alone, with primary endpoints including treatment adherence, kinesiophobia, heart rate variability, exercise tolerance, and psychological stress. The trial registration provides no compliance obligations or deadlines; it establishes the study design and enrollment parameters for future results dissemination.

For cardiac rehabilitation programs and clinical investigators, this registration signals growing interest in mind-body intervention integration for post-PCI recovery. Programs developing or expanding cardiac rehabilitation offerings may wish to monitor trial outcomes, as positive results could influence standard-of-care recommendations. No immediate action is required based on this registration alone.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Mindfulness-based Stress Reduction Combined With Aerobic Training in Cardiac Rehabilitation After Percutaneous Coronary Intervention: A Dual Impact on Kinesiophobia and Heart Rate Variability

N/A NCT07544459 Kind: NA Apr 22, 2026

Abstract

To evaluate the effectiveness of mindfulness-based stress reduction (MBSR) combined with aerobic training on treatment adherence, kinesiophobia, heart rate variability (HRV), exercise tolerance, and psychological stress response in patients with coronary heart disease (CHD) post-percutaneous coronary intervention (PCI).

Post-PCI patients (n = 150) were randomly assigned to an observation group (receiving combined MBSR and aerobic training) and a control group (receiving aerobic training only). Treatment adherence, the Tampa Scale for Kinesiophobia-Heart (TSK-SV Heart), HRV parameters, exercise tolerance, and psychological stress responses were assessed before and after the intervention. Psychological assessments included the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS).

Conditions: Coronary Heart Disease, Percutaneous Coronary Intervention, Mindfulness-based Stress Reduction, Aerobic Training, Kinesiophobia

Interventions: observation group

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Last updated

Classification

Agency
NIH
Published
April 22nd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Docket
NCT07544459

Who this affects

Applies to
Healthcare providers Clinical investigators Patients
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial conduct Cardiac rehabilitation Mind-body intervention
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Pharmaceuticals Public Health

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