Low Intensity Laser Therapy Study, Children, Pneumonia
Summary
Clinical trial NCT07552116 registered on ClinicalTrials.gov evaluates whether low intensity laser therapy combined with standard medical treatment improves immune response in children with Down syndrome (DS) and pneumonia. The randomized controlled study enrolled 40 DS children with bronchopneumonia, assigning 20 to receive low intensity laser therapy three times weekly for one month alongside inspiratory muscle training and medical treatment. Both groups had immune system markers (WBCs, IgG, IgA, IgM), respiratory rate, and oxygen saturation measured before and after the one-month treatment period.
“The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia.”
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What changed
Clinical trial NCT07552116 was registered on ClinicalTrials.gov to assess the impact of low intensity laser therapy on immune system response in children with Down syndrome (DS) who have pneumonia. The study employs a randomized controlled design with 40 participants split into two groups of 20 each. Group A receives low intensity laser therapy combined with inspiratory muscle training and standard medical treatment three times weekly for one month. Group B receives inspiratory muscle training and standard medical treatment only.
Healthcare providers and clinical investigators should note this trial as an emerging area of research exploring adjunctive laser therapy for respiratory infections in immunocompromised pediatric populations. The study measures immune response through WBC counts, immunoglobulin levels (IgG, IgA, IgM), respiratory rate, and oxygen saturation at baseline and one-month follow-up. Results may inform future treatment protocols but do not currently establish a standard of care.
Archived snapshot
Apr 28, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia
N/A NCT07552116 Kind: NA Apr 27, 2026
Abstract
Objective: The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, were included into ; group (A) received low intensity laser therapy, inspiratory muscle training in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.
Conditions: Pneumonia
Interventions: low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements, received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.
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