Kindred Web Program Improves African American Cancer Genetic Testing
Summary
NIH has registered clinical trial NCT07542405, a study evaluating whether the web-based program Kindred improves understanding of genetic cancer risk and cancer genetic testing among African American families. The trial targets hereditary cancer syndromes including BRCA1/2-related and Lynch syndrome. Participants receive internet-based and telephone-based interventions to learn about test results, risk reduction strategies, and family communication about cancer risk.
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What changed
NIH has registered clinical trial NCT07542405 titled 'A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families.' The trial will study an online educational tool providing information about hereditary cancer syndromes, genetic test results interpretation, and family communication about cancer risk. The study focuses on African Americans, a population shown to be less likely to engage in cancer genetic testing compared to other racial groups.
Healthcare providers and researchers focused on reducing health disparities in cancer genetic testing may find this trial relevant to watch. The study will enroll participants to receive internet-based and telephone-based interventions including discussion, survey administration, and structured education about BRCA1/2 and Lynch syndrome testing. No compliance obligations are created by this registry entry.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families
N/A NCT07542405 Kind: NA Apr 21, 2026
Abstract
This clinical trial studies whether a web-based program, Kindred, works to improve the understanding of genetic cancer risk and cancer genetic testing in African American families. Between 5% and 10% of all cancers are caused by genetic changes that are hereditary, which means that they run in families. Some kinds of cancer or a family history of cancer means individuals are more likely to have a genetic change. If a genetic change is identified in a family, other relatives can choose to undergo hereditary cancer genetic testing to better understand their cancer risk. In families where a genetic change is not identified, or results are uncertain, relatives may also benefit from discussing their cancer risk with providers and, in some cases, getting hereditary cancer genetic testing themselves. Research has shown that African Americans are less likely than other racial groups to engage in cancer genetic testing. Kindred is an online tool that provides information so individuals can learn about their cancer genetic test results, how cancer genetic testing can help individuals and families understand their overall cancer risk (and strategies for reducing risk), and ways to talk with each other about cancer risk and health. This may be an effective way to improve the understanding of genetic cancer risk and cancer genetic testing in African American families.
Conditions: BRCA1-Related Hereditary Breast and Ovarian Cancer Syndrome, BRCA2-Related Hereditary Breast and Ovarian Cancer Syndrome, Hereditary Neoplastic Syndrome, Lynch Syndrome
Interventions: Discussion, Internet-Based Intervention, Internet-Based Intervention, Survey Administration, Telephone-Based Intervention
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