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Prediction of Postoperative ICU Requirement in Oncologic Surgery

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Summary

NIH's ClinicalTrials.gov has registered NCT07542925, a prospective observational cohort study at a single tertiary oncology center comparing perioperative risk scoring systems for predicting postoperative ICU requirement in 500 adult oncologic surgery patients. The primary outcome is ICU admission within 24 hours post-surgery; secondary outcomes include unplanned ICU admission, ICU duration, mechanical ventilation need, hospital length of stay, and 30-day mortality.

“Accurate prediction of postoperative ICU admission is essential for optimizing patient safety and efficient allocation of limited critical care resources”

NIH , verbatim from source
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What changed

NIH's ClinicalTrials.gov has registered a prospective observational cohort study (NCT07542925) comparing perioperative risk scoring systems for predicting postoperative ICU requirement in 500 adult oncologic surgery patients. The study will evaluate ASA, SORT, CACI, P-POSSUM, ECOG, and NRS-2002 scoring systems as predictors of ICU admission within 24 hours post-surgery.

Healthcare institutions conducting oncologic surgery research should note this study's methodology for risk stratification. Clinical investigators enrolling oncologic surgery patients should be aware of this comparative evaluation of ICU prediction tools.

Archived snapshot

Apr 21, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Prediction of Postoperative ICU Requirement in Oncologic Surgery

Observational NCT07542925 Kind: OBSERVATIONAL Apr 21, 2026

Abstract

This prospective observational cohort study aims to compare the performance of commonly used perioperative risk scoring systems in predicting postoperative intensive care unit (ICU) requirement among adult patients undergoing oncologic surgery. Accurate prediction of postoperative ICU admission is essential for optimizing patient safety and efficient allocation of limited critical care resources, particularly in high-risk oncologic surgical populations.

A total of 500 adult patients scheduled for elective or emergency oncologic surgery will be prospectively enrolled at a single tertiary oncology center. Preoperative clinical and demographic data, intraoperative variables, and perioperative characteristics will be recorded using a standardized data collection form. Risk assessment will include the American Society of Anesthesiologists (ASA) Physical Status classification, Surgical Outcome Risk Tool (SORT), Age-adjusted Charlson Comorbidity Index (CACI), Portsmouth Physiological and Operative Severity Score for the enumeration of Mortality and morbidity (P-POSSUM), Eastern Cooperative Oncology Group (ECOG) performance status, Nutritional Risk Screening 2002 (NRS-2002), and preoperative serum albumin levels.

The primary outcome is the need for postoperative ICU admission within the first 24 hours after surgery. Secondary outcomes include unplanned ICU admission, duration of ICU stay, need for mechanical ventilation, hospital length of stay, and 30-day mortality. The predict...

Conditions: Neoplasms, Postoperative Complications, Perioperative/Postoperative Complications, Intensive Care Units

Interventions: Risk Assessment Scoring Systems (ASA, SORT, CACI, P-POSSUM, ECOG, NRS-2002)

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Last updated

Classification

Agency
NIH
Published
April 21st, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07542925

Who this affects

Applies to
Clinical investigators Healthcare providers Patients
Industry sector
6211 Healthcare Providers
Activity scope
Clinical research Risk assessment Patient enrollment
Threshold
500 adult patients undergoing elective or emergency oncologic surgery
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Compliance frameworks
GxP
Topics
Healthcare Public Health

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