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Miles for Mental Health Study, Group Exercise, Apr 21

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Summary

The NIH ClinicalTrials.gov registry has posted a new clinical study, NCT07541443, titled 'Miles for Mental Health,' examining whether combining group cardiovascular exercise with group therapy improves mental health outcomes in adults with generalized anxiety disorder and depressive disorders. The study will use exercise as the sole intervention type, with an enrollment period beginning April 21, 2026. This is an informational registry entry and does not create any regulatory obligations.

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What changed

The NIH ClinicalTrials.gov registry added a new clinical trial entry (NCT07541443) for a study titled 'Miles for Mental Health,' to be conducted using group exercise interventions. The study targets adults diagnosed with Generalized Anxiety Disorder and related depressive and anxiety disorders, with enrollment commencing April 21, 2026.

Healthcare providers, clinical investigators, and research institutions should be aware that this registry entry is informational only and does not impose any compliance obligations, reporting requirements, or regulatory mandates. Researchers studying similar interventions may use this entry to identify ongoing research in the mental health and exercise space.

Archived snapshot

Apr 21, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

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Miles for Mental Health

N/A NCT07541443 Kind: NA Apr 21, 2026

Abstract

Common mental health disorders, like anxiety and depression, are widespread among the American population. The prevalence of mental health disorders among adults continues has consistently increased from previous decades and is now a major public health challenge. Data shows that 1 in 5 Americans regularly report feeling depressed. Therapy is supported as an effective means of treating mental anxiety and depression, and lessening their severity. But therapy is expensive and not always covered by insurance. It is well known that exercise provides physiological and psychological benefits to those suffering from mental health disorders. However, prescribing and monitoring exercise can be challenging, if not impossible, for mental health practitioners, and individuals often are unsure how to begin an exercise program on their own. Studies that have investigated the impact on exercise on mental health have delivered exercise using a traditional clinical trial exercise structure, where exercise is completed by the client/patient under the supervision of a professional. This structure, while beneficial, does not always transfer well to real-world settings. Working one-on-one with an exercise professional poses financial and scheduling barriers for most. Few, if any, studies have used group exercise and group therapy to address mental health concerns. This study aims to combine cardiovascular exercise with group therapy to investigate the impact of cardiovascular fitness on mental...

Conditions: Generalized Anxiety Disorder (GAD), Depressive and Anxiety Disorders

Interventions: Exercise

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Classification

Agency
NIH
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Healthcare providers Clinical investigators
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trials Mental health treatment
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Healthcare Public Health

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