Oxadiazole HDAC6 inhibitors and uses thereof
Summary
The USPTO granted Patent US12590084B2 to Eikonizo Therapeutics, Inc. covering oxadiazole compounds that selectively inhibit HDAC6, a protein linked to cancer and neurological disorders including Alzheimer's disease. The patent includes 20 claims and covers pharmaceutical compositions and methods of treating HDAC6-related diseases. Inventors are Florence Fevrier Wagner and Thomas Edward Richardson.
What changed
Eikonizo Therapeutics received USPTO Patent US12590084B2 (Kind B2) for oxadiazole HDAC6 inhibitor compounds, methods of use, and associated pharmaceutical compositions. The patent, filed as Application No. 18132216 on April 7, 2023, and granted March 31, 2026, contains 20 claims under CPC classifications C07D 413/04, C07D 413/14, C07D 471/04, and C07D 487/04. The compounds target HDAC6, a protein implicated in cancer and neurological disorders.
Patent holders should document the grant date and maintain records for enforcement purposes. Competitors developing HDAC6 inhibitors should assess Freedom to Operate implications. No immediate compliance deadlines or regulatory reporting requirements are associated with this patent grant notice.
Archived snapshot
Mar 31, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Oxadiazole HDAC6 inhibitors and uses thereof
Grant US12590084B2 Kind: B2 Mar 31, 2026
Assignee
Eikonizo Therapeutics, Inc.
Inventors
Florence Fevrier Wagner, Thomas Edward Richardson
Abstract
Provided herein are compounds that selectively inhibit HDAC6, a protein whose activity is associated with a variety of diseases (e.g., cancer, neurological disorders). Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of treating HDAC6-related diseases and disorders (e.g., Alzheimer's disease, cancer) with the compounds in a subject, by administering the compounds and/or compositions described herein.
CPC Classifications
C07D 413/04 C07D 413/14 C07D 471/04 C07D 487/04
Filing Date
2023-04-07
Application No.
18132216
Claims
20
Named provisions
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Source
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