Oxadiazole HDAC6 inhibitors and uses thereof
Grant
US12590084B2
Kind: B2
Mar 31, 2026
Assignee
Eikonizo Therapeutics, Inc.
Inventors
Florence Fevrier Wagner, Thomas Edward Richardson
Abstract
Provided herein are compounds that selectively inhibit HDAC6, a protein whose activity is associated with a variety of diseases (e.g., cancer, neurological disorders). Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of treating HDAC6-related diseases and disorders (e.g., Alzheimer's disease, cancer) with the compounds in a subject, by administering the compounds and/or compositions described herein.
CPC Classifications
C07D 413/04
C07D 413/14
C07D 471/04
C07D 487/04
Filing Date
2023-04-07
Application No.
18132216
Claims
20