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Oxadiazole HDAC6 inhibitors and uses thereof

Grant US12590084B2 Kind: B2 Mar 31, 2026

Assignee

Eikonizo Therapeutics, Inc.

Inventors

Florence Fevrier Wagner, Thomas Edward Richardson

Abstract

Provided herein are compounds that selectively inhibit HDAC6, a protein whose activity is associated with a variety of diseases (e.g., cancer, neurological disorders). Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of treating HDAC6-related diseases and disorders (e.g., Alzheimer's disease, cancer) with the compounds in a subject, by administering the compounds and/or compositions described herein.

CPC Classifications

C07D 413/04 C07D 413/14 C07D 471/04 C07D 487/04

Filing Date

2023-04-07

Application No.

18132216

Claims

20