CREATE Medicines Genomic Integration Patent US12599678B2
Summary
The USPTO granted US Patent No. 12599678B2 to CREATE Medicines, Inc. on April 14, 2026, covering methods and compositions for modulating a target genome and stable integration of a transgene of interest into the genome of a cell. The patent application (No. 18313126) was filed on May 5, 2023, and contains 22 claims spanning CPC classifications including C12N 15/85, C12N 9/22, A61K 31/713, and C07K 14/7051, among others. Inventors include Daniel Getts, Yuxiao Wang, Namita Bisaria, Inna Shcherbakova, and Socheata Ly.
“Methods and composition for modulating a target genome and stable integration of a transgene of interest into the genome of a cell are disclosed.”
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GovPing monitors USPTO Patent Grants - Biotech (C12N) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 16 changes logged to date.
What changed
The USPTO issued US Patent No. 12599678B2 to CREATE Medicines, Inc., granting exclusive rights to methods and compositions for genomic integration and stable transgene insertion into cellular genomes. The patent, effective April 14, 2026, protects technology spanning multiple CPC classifications covering nucleic acid delivery systems, enzyme compositions, and therapeutic applications.
Competitors developing genomic integration technologies should conduct freedom-to-operate analyses to assess potential infringement risks. Licensees and investors in gene therapy or cell engineering fields may find this patent relevant to existing or planned therapeutic programs.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Methods and compositions for genomic integration
Grant US12599678B2 Kind: B2 Apr 14, 2026
Assignee
CREATE Medicines, Inc.
Inventors
Daniel Getts, Yuxiao Wang, Namita Bisaria, Inna Shcherbakova, Socheata Ly
Abstract
Methods and composition for modulating a target genome and stable integration of a transgene of interest into the genome of a cell are disclosed.
CPC Classifications
C12N 15/85 C12N 9/1276 C12N 9/22 C12N 15/11 C12N 15/113 C12N 15/907 C12N 2310/14 C12N 2310/20 C12N 2320/31 C12N 2800/80 C12N 2800/90 C12N 2830/50 C12N 2840/203 A61K 31/711 A61K 31/713 A61K 38/1774 A61K 38/45 A61K 38/465 A61K 39/39558 A61K 48/00 C07K 14/7051 C07K 16/32 C07K 2319/03 C07K 2319/09 C07K 2319/30 C07K 2319/33 C12Y 207/07049
Filing Date
2023-05-05
Application No.
18313126
Claims
22
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