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Fused Amino Pyrimidine Compounds Treat Tinnitus, Hearing Loss, Meniere's

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Summary

USPTO published Patent Application US20260108529A1 on April 23, 2026, filed by inventor Zhong Zhong on October 23, 2025 (Application No. 19366802), covering fused amino pyrimidine compounds for treating tinnitus, acute sensorineural hearing loss, age-related hearing loss, and Meniere's disease. The application discloses therapeutic compositions containing compounds according to Formula (I) or their pharmaceutically acceptable salts, classified under CPC codes A61K 31/5377, A61K 31/519, A61K 31/5517, A61K 45/06, and A61P 27/16.

“Methods of treating tinnitus, acute sensorineural hearing loss, age-related hearing loss, or Meniere's disease, with a compound according to Formula (I), or a pharmaceutically acceptable salt thereof, are provided.”

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About this source

USPTO classification A61K covers pharmaceutical preparations: formulations, dosage forms, combination therapies, delivery systems, and the vehicles that carry active ingredients. Every newly published application in A61K lands in this feed, around 245 a month. Applications publish 18 months after filing, so this feed reveals what pharma formulators at major sponsors and generics were working on in the prior year and a half. Watch this if you compete in drug formulation, file freedom-to-operate analyses, scout competitive drug products before clinical readouts, or follow novel delivery platforms like nanoparticles, lipid carriers, and long-acting injectables.

What changed

USPTO published Patent Application US20260108529A1 disclosing fused amino pyrimidine compounds according to Formula (I) and their use in treating tinnitus, acute sensorineural hearing loss, age-related hearing loss, and Meniere's disease. The application also covers therapeutic compositions containing these compounds or their pharmaceutically acceptable salts. Filing date was October 23, 2025, with Application No. 19366802.

Patent applications are informational publications that establish priority rights and disclose the invention for public notice. They do not create immediate compliance obligations. Third parties reviewing this publication should note the therapeutic claims and CPC classifications (A61K 31/5377, A61K 31/519, A61K 31/5517) to assess potential freedom-to-operate considerations or competitive landscape for similar pharmaceutical compounds.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

FUSED AMINO PYRIMIDINE COMPOUNDS FOR TREATMENT OF TINNITUS, ACUTE SENSORINEURAL HEARING LOSS, AGE-RELATED HEARING LOSS, AND MENIERE'S DISEASE

Application US20260108529A1 Kind: A1 Apr 23, 2026

Inventors

Zhong Zhong

Abstract

Methods of treating tinnitus, acute sensorineural hearing loss, age-related hearing loss, or Meniere's disease, with a compound according to Formula (I), or a pharmaceutically acceptable salt thereof, are provided. Also provided are therapeutic compositions that may be used to improve one or more symptoms of tinnitus, acute sensorineural hearing loss, or Meniere's disease. or pharmaceutically acceptable salts thereof, wherein R1, R2, R7 and ring A have any of the meanings herein defined in the description.

CPC Classifications

A61K 31/5377 A61K 31/519 A61K 31/5517 A61K 45/06 A61P 27/16

Filing Date

2025-10-23

Application No.

19366802

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260108529A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent filing Pharmaceutical compounds
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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