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Crystalline Forms of Formula (I) Compounds for Cancer Treatment

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Summary

The USPTO granted Patent US12606553B2 to Foghorn Therapeutics Inc., covering crystalline forms of a formula (I) compound and compositions containing those forms. The patent also protects methods of using the crystalline forms for treating cancer in subjects, including administration of an effective amount of the compound. The patent, classified under CPC C07D 417/14 (organic chemistry, heterocyclic compounds), contains 11 claims.

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What changed

The USPTO issued Patent US12606553B2 to Foghorn Therapeutics Inc., granting exclusive rights to crystalline forms of a formula (I) compound and pharmaceutical compositions containing those forms. The patent also covers methods of treating cancer by administering an effective amount of the crystalline compound to a subject in need thereof. The patent contains 11 claims and was filed on March 9, 2022, with application number 18281022.

Pharmaceutical manufacturers and drug developers should be aware that Foghorn Therapeutics now holds exclusive rights to these specific crystalline forms and their therapeutic applications. Any entity seeking to develop competing cancer treatments using similar crystalline forms would need to design around this patent or seek a licensing arrangement with Foghorn. The patent's broad 'methods of treating cancer' claim language suggests potential enforcement risks for generic or biosimilar developers working in this chemical space.

Archived snapshot

Apr 21, 2026

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← USPTO Patent Grants

Crystalline forms, compositions containing same, and methods of their use

Grant US12606553B2 Kind: B2 Apr 21, 2026

Assignee

FOGHORN THERAPEUTICS INC.

Inventors

Rishi G. Vaswani, Chong-Hui Gu

Abstract

Disclosed are crystalline forms of the compound of formula (I): (I) Also disclosed are compositions containing the crystalline forms of the compound of formula (I) and methods of their use. The methods may be for treating cancer in a subject in need thereof, e.g., by administering to the subject an effective amount of the crystalline form disclosed herein or its composition.

CPC Classifications

C07D 417/14

Filing Date

2022-03-09

Application No.

18281022

Claims

11

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Last updated

Classification

Agency
USPTO
Published
April 21st, 2026
Instrument
Rule
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12606553B2

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent grant Cancer treatment Drug formulation
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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