Fixed Bed Cell Culture and Harvesting System
Summary
USPTO published patent application US20260109929A1 on April 23, 2026, filed December 19, 2025 (Application No. 19427412). The application covers a fixed bed cell culture and harvesting system invented by Vasiliy Nikolaevich Goral, Kathleen Anne Krebs, William Joseph Lacey, Mackenzie Anna Maloney, and Todd Marshall Wetherill. The system includes a cell culture vessel, a piston with an airtight seal, and a driver mechanism to pressurize the cavity for harvesting cells through a port. CPC classifications span C12M and C12N ranges.
“A cell culture system is provided that includes a cell culture vessel having an interior cavity to house a cell culture substrate in a cell culture space, and at least one port for at least one of fluid inlet to the interior cavity and fluid outlet from the interior cavity.”
About this source
GovPing monitors USPTO Patent Applications - Biotech (C12N) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 263 changes logged to date.
What changed
USPTO published patent application US20260109929A1 disclosing a fixed bed cell culture system and methods for harvesting cells. The system includes a cell culture vessel with an interior cavity to house a cell culture substrate, a piston with a distal end sealed with an airtight seal above the cell culture space, and a driver coupled to the piston to move it and pressurize the interior cavity to harvest cells through at least one port.
Biotechnology and pharmaceutical researchers, as well as companies developing cell culture and bioprocessing technologies, should review this publication to assess freedom-to-operate considerations, potential licensing opportunities, and the competitive landscape for cell culture harvesting systems.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
FIXED BED CELL CULTURE AND HARVESTING SYSTEM AND METHODS OF USING THE SAME
Application US20260109929A1 Kind: A1 Apr 23, 2026
Inventors
Vasiliy Nikolaevich Goral, Kathleen Anne Krebs, William Joseph Lacey, Mackenzie Anna Maloney, Todd Marshall Wetherill
Abstract
A cell culture system is provided that includes a cell culture vessel having an interior cavity to house a cell culture substrate in a cell culture space, and at least one port for at least one of fluid inlet to the interior cavity and fluid outlet from the interior cavity. The system further includes a piston having a distal end disposed in the cell culture vessel above the cell culture space, the distal end of the piston being sealed with an airtight seal within the interior cavity. The system also includes a driver coupled to the piston to move the piston so as to increase and decrease a distance between the distal end and the cell culture space. The driver can pressurize the interior cavity via actuation of the piston to harvest cells from the cell culture space through the at least one port.
CPC Classifications
C12M 33/04 C12M 23/20 C12M 25/14 C12M 29/10 C12M 33/12 C12N 2513/00 C12N 2533/30
Filing Date
2025-12-19
Application No.
19427412
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