Femoral Artery Block Trial for Tourniquet Pain in Below Knee Surgery
Summary
NIH has registered NCT07548567, a prospective, randomized, double-blind controlled trial evaluating ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a saline control for managing tourniquet-induced hypertension in adult patients undergoing below-the-knee fracture surgery. The study will enroll ASA I-III patients receiving standardized sciatic nerve block and total intravenous anesthesia, with primary outcomes assessing long-axis FAB effectiveness in reducing tourniquet-induced hypertension. Secondary outcomes include hemodynamic stability, analgesic requirements, pain scores, block characteristics, and procedural performance metrics.
“This is a prospective, randomized, double-blind controlled trial evaluating an ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a control group.”
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What changed
This document registers a new prospective, randomized, double-blind controlled clinical trial on ClinicalTrials.gov. The study evaluates ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a saline control group for managing tourniquet pain and hypertension in adult patients undergoing below-the-knee fracture surgery. Participants (ASA I-III) will be randomized into three groups: short-axis FAB, long-axis FAB, or control (normal saline injection).
Affected parties — clinical investigators, anesthesiologists, orthopedic surgeons, and hospitals conducting tourniquet-based below-knee procedures — should be aware of this trial's outcomes upon completion, as FAB technique comparisons may inform regional anesthesia protocols for similar procedures.
Archived snapshot
Apr 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
A LONG AXIS APPROACH TO THE FEMORAL ARTERY BLOCK (FAB), FOR MANAGING TOURNIQUET PAIN AND HYPERTENSION IN BELOW-THE-KNEE FRACTURES SURGERY.
N/A NCT07548567 Kind: NA Apr 23, 2026
Abstract
This is a prospective, randomized, double-blind controlled trial evaluating an ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a control group.
The study will include adult patients (ASA I-III) undergoing below-the-knee fracture surgery with tourniquet application. All patients will receive standardized anesthesia including sciatic nerve block and total intravenous anesthesia.
Participants will be randomized into three groups: short-axis FAB, long-axis FAB, or control (saline injection). The primary aim is to assess the effectiveness of the long-axis FAB in reducing tourniquet-induced hypertension. Secondary outcomes include hemodynamic stability, analgesic requirements, pain scores, block characteristics, and procedural performance metrics.
Conditions: Tourniquet Hypertension
Interventions: Femoral artery block - short-axis, Femoral artery block - long-axis, Normal saline injection (control)
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