Changeflow GovPing Healthcare & Life Sciences European Patent EP4433476A1: Chromane Amidine A...
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European Patent EP4433476A1: Chromane Amidine Antibiotics, Merck, Apr 2026

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Summary

The European Patent Office published patent application EP4433476A1 for chromane amidine monobactam antibiotics on April 15, 2026, designated Kind A1 (application published with search report). The applicant is Merck Sharp & Dohme LLC, with listed inventors CHEN, Helen, Y., DONG, Shuzhi, HU, Zhiyong, SU, Jing, YU, Tao, and ZHANG, Yong. The application claims pharmaceutical compositions comprising the disclosed chromane amidine compounds classified under C07D 417/14 for the treatment of bacterial infections, designated across 35 validation states including all EU member states, the UK, and additional European countries.

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About this source

GovPing monitors EPO Patent Bulletin - Organic Chemistry (C07D) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 43 changes logged to date.

What changed

The EPO published patent application EP4433476A1 for chromane amidine monobactam antibiotic compounds and pharmaceutical compositions comprising them, with the application designated as Kind A1 indicating a published search report. The technical disclosure covers chromane amidine derivatives classified under IPC subclass C07D 417/14, with secondary classifications in A61K 31/427 (pharmaceutical compositions) and A61P 31/04 (anti-infective agents).

Pharmaceutical companies and biotech firms engaged in antibiotic development should review the technical disclosure to assess potential freedom-to-operate considerations and to identify opportunities for licensing or design-around strategies. The designated validation states covering all EU member states plus the UK, Switzerland, Norway, and other European countries mean the application could result in patents with market exclusivity across a broad territory if granted after examination.

Archived snapshot

Apr 25, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← EPO Patent Bulletin

CHROMANE AMIDINE MONOBACTAM ANTIBIOTICS

Publication EP4433476A1 Kind: A1 Apr 15, 2026

Applicants

Merck Sharp & Dohme LLC

Inventors

CHEN, Helen, Y., DONG, Shuzhi, HU, Zhiyong, SU, Jing, YU, Tao, ZHANG, Yong

IPC Classifications

C07D 417/14 20060101AFI20230526BHEP A61K 31/427 20060101ALI20230526BHEP A61P 31/04 20060101ALI20230526BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Last updated

Classification

Agency
EPO
Published
April 15th, 2026
Instrument
Rule
Branch
International
Legal weight
Binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies Manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application publication Antibiotic compound research Pharmaceutical IP
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Regulatory Affairs
Topics
Pharmaceuticals Healthcare

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