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Endoscopic Assessment of Schneiderian Membrane Perforation During Osseodensification-Mediated Transcrestal Sinus Floor Elevation

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Summary

The National Institutes of Health registered a pilot clinical trial (NCT07542275) on ClinicalTrials.gov evaluating Schneiderian membrane perforation rates during osseodensification-mediated transcrestal sinus floor elevation with simultaneous graftless implant placement. The study will monitor membrane response and assess effects of Densah burs on membrane distention under sinuscopic control.

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What changed

A new clinical trial registration was added to ClinicalTrials.gov for a pilot study evaluating endoscopic assessment of Schneiderian membrane perforation during osseodensification-mediated transcrestal sinus floor elevation. The study will use Densah burs without bone graft material and perform simultaneous implant placement under sinuscopic control monitored by an ENT specialist.

Affected parties include dental implant researchers, oral surgeons, and ENT specialists involved in sinus floor elevation procedures. This registration does not create compliance obligations but provides notice of an upcoming research activity in the field of dental implantology.

Archived snapshot

Apr 21, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

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Endoscopic Assessment of Schneiderian Membrane Perforation During Osseodensification-mediated Transcrestal Sinus Floor Elevation With Graftless Immediate Implant Placement in Subsinus Bone Height of 4-6 mm: A Pilot Study, Performed by an Inexperienced OD-surgeon

N/A NCT07542275 Kind: NA Apr 21, 2026

Abstract

This present study will evaluate Schneiderian membrane perforation rates using osseodensification in TSFE with simultaneous graftless implant placement, under sinuscopic control monitored by an ENT specialist.

An endoscopic evaluation will be continuously conducted throughout the surgical procedure. TSFE will be performed using Densah burs without the addition of bone graft material, followed by implant placement. The rationale behind this approach is to monitor the response of the Schneiderian membrane and assess the effects of Densah burs on membrane distention and the occurrence of SMP.

Conditions: Sinusitis, Periodontal Disease

Interventions: Scheiderian Membrane Perforation

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Last updated

Classification

Agency
NIH
Published
April 21st, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Healthcare providers Clinical investigators
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Dental implant placement Sinus floor elevation
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Compliance frameworks
GxP
Topics
Medical Devices Pharmaceuticals

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