Docking Peptides for Targeted Antibody Drug Conjugates
Summary
USPTO published patent application US20260109780A1 filed by inventors John K. Cini and Nick Evans on April 22, 2025, covering novel docking peptides and antibody-based drug conjugates designed for enhanced targeted delivery of drug payloads to tumor microenvironments with controlled drug-to-antibody ratios. The application includes CPC classifications indicating therapeutic applications for cancer treatment (A61P 35/00).
“Provided herein are novel docking peptides and antibody-based drug conjugates that include such docking peptides.”
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GovPing monitors USPTO Patent Applications - Therapeutics (A61P) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 219 changes logged to date.
What changed
USPTO published patent application US20260109780A1 disclosing novel docking peptides enabling controlled attachment of drug moieties and tumor-targeting moieties in antibody-based drug conjugates. The invention aims to enhance targeted delivery of drug payloads to tumor microenvironments with a controlled drug-to-antibody ratio (DAR). CPC classifications indicate pharmaceutical and peptide chemistry applications, with therapeutic use in cancer treatment (A61P 35/00).
For parties in the pharmaceutical or biotechnology sector working on antibody-drug conjugates or targeted drug delivery systems, this patent application establishes prior art in docking peptide technology and controlled DAR conjugation methods. Companies developing similar targeted therapeutic platforms should review the claimed peptide structures and conjugation approaches to assess potential freedom-to-operate considerations.
Archived snapshot
Apr 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
DOCKING PEPTIDES AND RELATED ANTIBODY-BASED DRUG CONJUGATES
Application US20260109780A1 Kind: A1 Apr 23, 2026
Inventors
John K. Cini, Nick Evans
Abstract
Provided herein are novel docking peptides and antibody-based drug conjugates that include such docking peptides. In embodiments, the subject docking peptide allows for the controlled attachment of one or more drug moieties and a tumor targeting moiety that allows for the targeting of the drug moiety to the tumor microenvironment. In some embodiments, the antibody-based drug conjugates provided herein advantageously allows for enhanced targeted delivery of a drug payload having a controlled drug-to-antibody ratio (DAR) to a target site.
CPC Classifications
C07K 16/32 A61K 47/66 A61K 47/68031 A61K 47/6855 A61K 47/6889 A61P 35/00 C07K 2317/622 C07K 2319/09
Filing Date
2025-04-22
Application No.
19186382
Parties
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