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DCTY Biotech EGFRvIII CAR Antibody Application, Apr 23

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Summary

Beijing DCTY Biotech Co., Ltd. has filed Application US20260108607A1 with the USPTO covering an antibody targeting EGFRvIII and its use in chimeric antigen receptor (CAR) cell immunotherapy. The application, filed August 4, 2023 under Application No. 19100824, names Shuang Li, Zishan Zhou, Yujie Song, and Rong Zhang as inventors. The published application provides claims to the antibody or antigen-binding fragment thereof, a CAR incorporating the fragment, and therapeutic and detection uses. Biopharmaceutical companies developing CAR-T or targeted cancer immunotherapies targeting EGFRvIII should review this published application for potential freedom-to-operate considerations.

“Provided is an antibody targeting EGFRvIII or an antigen-binding fragment thereof.”

USPTO , verbatim from source
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About this source

USPTO classification A61K covers pharmaceutical preparations: formulations, dosage forms, combination therapies, delivery systems, and the vehicles that carry active ingredients. Every newly published application in A61K lands in this feed, around 245 a month. Applications publish 18 months after filing, so this feed reveals what pharma formulators at major sponsors and generics were working on in the prior year and a half. Watch this if you compete in drug formulation, file freedom-to-operate analyses, scout competitive drug products before clinical readouts, or follow novel delivery platforms like nanoparticles, lipid carriers, and long-acting injectables.

What changed

Beijing DCTY Biotech Co., Ltd. has published Application US20260108607A1 covering an antibody targeting EGFRvIII (or an antigen-binding fragment thereof), a CAR comprising that fragment, and methods of treating or detecting conditions using the foregoing. The application, with a filing date of August 4, 2023, names four inventors and includes CPC classifications spanning A61K (pharmaceutical compositions) and C07K (proteins/peptides), indicating therapeutic and immunological applications.\n\nBiopharmaceutical companies engaged in CAR-T development, targeted cancer immunotherapy, or EGFRvIII-directed oncology programs should monitor this published application for claims that may overlap with their own pipeline assets. While the application has not yet matured into an issued patent, it establishes a priority date that could affect later-filed applications in this technological space.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

ANTIBODY TARGETING EGFRVIII AND USE THEREOF IN CELL IMMUNOTHERAPY

Application US20260108607A1 Kind: A1 Apr 23, 2026

Assignee

BEIJING DCTY BIOTECH CO., LTD.

Inventors

Shuang LI, Zishan ZHOU, Yujie SONG, Rong ZHANG

Abstract

Provided is an antibody targeting EGFRvIII or an antigen-binding fragment thereof. Further provided are a CAR comprising the antigen-binding fragment targeting EGFRvIII, and treatment and detection use thereof.

CPC Classifications

A61K 40/4204 A61K 40/11 A61K 40/15 A61K 40/31 C07K 14/7051 C07K 16/2863 C07K 2317/24

Filing Date

2023-08-04

Application No.

19100824

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254.1 Biotechnology
Activity scope
Patent filing Biotechnology R&D Cancer immunotherapy
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Regulatory Affairs
Topics
Pharmaceuticals Public Health

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