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Circadian Meal Timing Effect on Postprandial Glucose

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Summary

The NIH ClinicalTrials.gov registry added a randomized crossover study (NCT07545330) investigating the effect of circadian timing of a standardized meal on postprandial glucose response in healthy adults. The study will compare morning versus evening meal consumption, assessing glucose via incremental area under the curve (iAUC) over 120 minutes. Participants are healthy adults enrolled in a crossover design allowing each subject to serve as their own control.

“This randomized crossover study aims to investigate the effect of circadian timing of a standardized meal (morning versus evening consumption) on postprandial glucose response in healthy adults.”

NIH , verbatim from source
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About this source

ClinicalTrials.gov is the NIH-run registry of every clinical trial conducted in the United States, plus most international trials sponsored by US-based companies or institutions. By federal law, sponsors must register Phase 2 through Phase 4 studies before enrolling patients and post results within a year of completion. This feed tracks every new trial registration and study update, around 700 a month: drug interventions, device studies, behavioral protocols, observational research. Watch this if you scout drug candidates moving into mid or late-stage development, monitor competitor pipelines, or follow rare disease research where new trials signal patient hope. GovPing parses sponsor, phase, intervention, and target indication on each entry.

What changed

The NIH registered a new clinical trial on ClinicalTrials.gov studying how meal timing (morning versus evening) affects postprandial glucose levels in healthy adults. The study uses a randomized crossover design where participants will consume a standardized test meal at different times of day, with glucose measured via incremental area under the curve (iAUC) over 120 minutes. This is a registry entry for an observational/interventional clinical study and does not create regulatory obligations for external parties.

Healthcare providers and clinical researchers involved in metabolic, nutritional, or circadian-rhythm research may find this trial relevant to ongoing work in these areas. The study registration provides protocol details without imposing compliance requirements on other entities.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Effect of Circadian Timing of a Standardized Meal on Postprandial Glucose Response in Healthy Adults

N/A NCT07545330 Kind: NA Apr 22, 2026

Abstract

This randomized crossover study aims to investigate the effect of circadian timing of a standardized meal (morning versus evening consumption) on postprandial glucose response in healthy adults. Postprandial glucose will be assessed using the incremental area under the curve (iAUC) over 120 minutes.

Conditions: Meal Timing, Postprandial Glucose, Glycemic Response to Feeding in Healthy Participants

Interventions: Standardized Test Meal

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Last updated

Classification

Agency
NIH
Published
April 22nd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Healthcare providers Clinical investigators Patients
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Glucose metabolism research Nutritional study
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Pharmaceuticals Public Health Biotechnology

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