Cervical Lordosis Study Compares Standing Radiographs vs MRI

NIH registered a new observational clinical trial (NCT07541586) on ClinicalTrials.gov, establishing a study to compare cervical lordosis measurements obtained from standing lateral radiographs versus supine MRI in individuals without structural cervical pathology. The study additionally examines whether T1 slope independently contributes to cervical alignment and whether imaging modality significantly alters measured lordosis values. Healthcare providers and clinical investigators conducting or commissioning cervical imaging research should be aware that this study may inform future imaging protocol decisions and measurement standards. As an observational study with no interventions, it does not impose any compliance obligations on registered entities.