Cells Resistant to Mobile Genetic Elements
Summary
USPTO published patent application US20260109938A1, filed July 19, 2023, covering cells resistant to mobile genetic elements and methods for obtaining them. The invention includes orthogonal genetic code systems designed to prevent horizontal gene transfer, with potential applications in protecting engineered cells and preventing unwanted genetic exchange. Inventors are Jason CHIN, Jerome ZURCHER, and Wesley ROBERTSON.
“Provided are cells that are resistant to mobile genetic elements or horizontal gene transfer, and methods for obtaining said cells.”
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GovPing monitors USPTO Patent Applications - Biotech (C12N) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 264 changes logged to date.
What changed
USPTO published patent application US20260109938A1 on April 23, 2026, for cells resistant to mobile genetic elements and methods of obtaining such cells. The application covers new genetic code schemes and orthogonal systems designed to prevent horizontal transfer of genetic information. CPC classifications span C12N (microbiology), C12P (fermentation), and C12R (microorganism classification).
Biotechnology manufacturers and pharmaceutical companies developing engineered cells should monitor this application for competitive intelligence on orthogonal genetic code approaches. While patent applications do not create immediate compliance obligations, they signal emerging technologies in genetic engineering that may inform future research and development strategies.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
GENETIC CODES
Application US20260109938A1 Kind: A1 Apr 23, 2026
Inventors
Jason CHIN, Jerome ZURCHER, Wesley ROBERTSON
Abstract
Provided are cells that are resistant to mobile genetic elements or horizontal gene transfer, and methods for obtaining said cells. Also provided are methods for preventing the horizontal transfer of genetic information between a mobile genetic element and a first cell, cells making use of new genetic codons schemes and related subject matter, kits comprising mutually orthogonal cells, and mobile genetic elements. Also provided are methods of altering the susceptibility of a gene to mutations that alter the encoded amino acid sequence, methods for evolving or improving a protein, and methods for rendering a target gene more resistant to mutation. Additionally provided are uses of the cells for making polymers and methods comprising using the cells for making polymers.
CPC Classifications
C12N 1/20 C12N 1/36 C12N 15/70 C12P 1/04 C12R 2001/19
Filing Date
2023-07-19
Application No.
18993813
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