Bacteriophage Patent, Bacterial Wilt Control, PANEFRI, Apr 14
Summary
USPTO granted Patent US12599142B2 to PANEFRI INDUSTRIAL CO., LTD. on April 14, 2026, covering bacteriophages comprising a tail fiber protein with a C terminus host recognition site (SEQ ID NO: 1) that infect Ralstonia solanacearum, the pathogen causing bacterial wilt disease in plants. The patent contains 20 claims and protects compositions and methods for preventing or treating bacterial wilt disease in a wide variety of plant hosts.
“Bacteriophages that comprise a tail fiber protein sequence comprising a C terminus host recognition site described by SEQ ID NO: 1 and which infect Ralstonia solanacearum which causes bacterial wilt disease are disclosed.”
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What changed
USPTO granted Patent US12599142B2 to PANEFRI INDUSTRIAL CO., LTD., covering bacteriophages with a tail fiber protein sequence comprising a C terminus host recognition site described by SEQ ID NO: 1 that infect Ralstonia solanacearum, the causative agent of bacterial wilt disease. The patent protects compositions comprising these bacteriophages as wilt control agents and methods for preventing or treating bacterial wilt disease in plants.
For parties interested in agricultural biocontrol, plant pathology, or crop protection technology, this grant establishes enforceable intellectual property rights in the United States for phage-based bacterial wilt disease control. The patent's broad claim scope covering methods for preventing or treating diseases caused by Ralstonia solanacearum may affect research, product development, and licensing discussions in the agricultural biocontrol space.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Bacteriophage, bacterial wilt disease control agent, and bacterial wilt disease control method
Grant US12599142B2 Kind: B2 Apr 14, 2026
Assignee
PANEFRI INDUSTRIAL CO., LTD.
Inventors
Toshiaki Harashima, Kazuma Nakano, Toru Karimata, Kumiko Hokama
Abstract
Bacteriophages that comprise a tail fiber protein sequence comprising a C terminus host recognition site described by SEQ ID NO: 1 and which infect Ralstonia solanacearum which causes bacterial wilt disease are disclosed. Compositions comprising these bacteriophages may be employed as wilt control agents. Methods for preventing or treating diseases caused by Ralstonia solanacearum such as bacterial wilt disease are also disclosed. A bacterial wilt disease control method in a plant may include administering such bacteriophages to a plant or to a plant growth medium and can be effective against a wide variety of Ralstonia solanacearum strains. Nucleic acids encoding the C terminus host recognition site and amino acid sequences comprising the host recognition site are also disclosed.
CPC Classifications
A01N 63/40 A01P 1/00 A01P 3/00 C07K 14/005 C07K 14/01 C12N 7/00 C12N 2795/10221 C12N 2795/10222 C12N 2795/10232 C12N 2795/10271
Filing Date
2020-07-30
Application No.
18007432
Claims
20
Parties
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