Changeflow GovPing Healthcare & Life Sciences Anvisa Approves VYVGART for Myasthenia Gravis a...
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Anvisa Approves VYVGART for Myasthenia Gravis and DIAGTOC Radiopharmaceutical

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Summary

ANVISA published the registration approval for VYVGART® (alfaefgartigimode) as an adjunct to standard therapy for adult patients with generalized myasthenia gravis (MGg) who are anti-acetylcholine receptor (AChR) antibody positive. ANVISA also approved DIAGTOC (edotreotida), a radiopharmaceutical for diagnostic use in neuroendocrine tumors and organs including liver, spleen, pituitary gland, thyroid, and kidneys. Both registrations were published on April 27, 2026, in Diário Oficial da União via Resolução RE 1.682.

“O uso do produto foi autorizado como complemento à terapia padrão para o tratamento de pacientes adultos com miastenia gravis generalizada (MGg) positivos para anticorpos anti-receptor de acetilcolina (AChR).”

ANVISA , verbatim from source
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About this source

GovPing monitors Brazil ANVISA for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 18 changes logged to date.

What changed

ANVISA granted market registration to two pharmaceutical products. VYVGART® (alfaefgartigimode) is approved as adjunct therapy for adults with generalized myasthenia gravis who test positive for anti-acetylcholine receptor antibodies. DIAGTOC (edotreotida) is approved as a diagnostic radiopharmaceutical for neuroendocrine tumors and organs including the liver, spleen, pituitary gland, thyroid, and kidneys.\n\nHealthcare providers prescribing treatments for myasthenia gravis may consider VYVGART as a newly available therapeutic option in Brazil. Pharmaceutical distributors and hospital pharmacies should update their formularies to include these newly registered products. The registrations were formalized via Resolução RE 1.682 published in the Diário Oficial da União.

Archived snapshot

Apr 27, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

NOVOS MEDICAMENTOS

Anvisa aprova registro de mais um produto para miastenia gravis

VYVGART® é indicado como complemento à terapia padrão Compartilhe: Publicado em 27/04/2026 14h51 Atualizado em 27/04/2026 15h06

Foto: Freepik

A Agência Nacional de Vigilância Sanitária (Anvisa) publicou, nesta segunda-feira (27/4), o registro do medicamento VYVGART® (alfaefgartigimode). O uso do produto foi autorizado como complemento à terapia padrão para o tratamento de pacientes adultos com miastenia gravis generalizada (MGg) positivos para anticorpos anti-receptor de acetilcolina (AChR).

A MGg é uma doença autoimune que tem como principal característica é fraqueza muscular que melhora com o repouso e piora com o exercício ou ao longo do dia. A grande maioria dos pacientes apresenta manifestações oculares como ptose ou diplopia e, destes casos, cerca de metade desenvolve doença generalizada em dois anos.

Radiofármaco

Outro medicamento que teve registro publicada nesta segunda (27/4) foi o DIAGTOC ( edotreotida ). O produto é um radiofármaco destinado exclusivamente ao uso diagnóstico de tumores neuroendócrinos e também em órgãos como fígado, baço, glândula pituitária, tireoide e rins.

O uso desses medicamentos possui um histórico amplo, sendo utilizados há mais de cinquenta anos no Brasil, com aplicação nas mais diversas áreas clínicas, como oncologia, cardiologia, nefrologia, ortopedia, neurologia etc.

Leia a R esoluç ão (RE) 1.682 publicada no Diário Oficial da União (DOU).

Categoria Saúde e Vigilância Sanitária
Tags: novo medicamento radiofármaco miastenia gravis Compartilhe:

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Last updated

Classification

Agency
ANVISA
Published
April 27th, 2026
Instrument
Notice
Branch
Executive
Source language
pt
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Patients
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug approval Drug registration Pharmaceutical distribution
Geographic scope
Brazil BR

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Clinical Operations
Topics
Public Health

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