AI Estimates Biological Age from Facial, Tongue, Retina
Summary
The USPTO published patent application US20260112504A1, filed December 10, 2025, for methods, devices, and systems that use a multi-modal transformer-based architecture with cross-attention combining facial, tongue, and retina images to estimate biological age (BA). The resulting AgeDiff metric (chronological age minus biological age) can function as a standalone biomarker or combine with other factors for chronic disease risk stratification and progression prediction. Inventors are Yuanxu GAO and Kang ZHANG, with application number 19414736.
“Provided herein in some embodiments are methods, devices, storage media, and systems using a model having a multi-modal transformer-based architecture with cross-attention which combines facial, tongue and retina images to estimate biological age (BA).”
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GovPing monitors USPTO Patent Applications - Health Informatics (G16H) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 137 changes logged to date.
What changed
The USPTO published a patent application for an AI-driven biological age estimation method. The invention uses a multi-modal transformer-based model with cross-attention mechanisms to process facial, tongue, and retina images simultaneously, producing a biological age estimate that differs from chronological age.
Affected parties include technology companies developing AI health-assessment tools, medical device manufacturers, and healthcare providers deploying diagnostic AI systems. While this publication creates no immediate compliance obligations, it establishes prior art in the AI health-diagnostics space and may influence future patent strategies and competitive positioning for organizations working in biological age estimation or multi-modal health assessment.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
METHODS, DEVICES, AND SYSTEMS FOR ESTIMATION OF BIOLOGICAL AGE
Application US20260112504A1 Kind: A1 Apr 23, 2026
Inventors
Yuanxu GAO, Kang ZHANG
Abstract
Provided herein in some embodiments are methods, devices, storage media, and systems using a model having a multi-modal transformer-based architecture with cross-attention which combines facial, tongue and retina images to estimate biological age (BA). The difference between chronological age (CA) and BA (AgeDiff) can be used as a standalone biomarker, or conjunctively alongside other known factors for risk stratification and progression prediction of chronic diseases.
CPC Classifications
G16H 50/30 G06N 3/045 G16H 30/40
Filing Date
2025-12-10
Application No.
19414736
Parties
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