ADEPT Diarrhea Prediction Tool Pilot, LMICs
Summary
NIH has registered a pilot before-after feasibility trial testing the Accessible Diarrhea Etiology Prediction Tool (ADEPT), a mobile phone-based clinical decision-support application, among informally trained healthcare providers in low- and middle-income countries. The study aims to assess the tool's acceptability, feasibility, and utility in reducing inappropriate antibiotic prescribing for pediatric diarrhea. Participants will use the ADEPT application during routine patient care, with outcomes measured before and after implementation.
What changed
NIH registered a clinical trial (NCT07538531) evaluating the ADEPT mobile application as a clinical decision-support tool for informal healthcare providers treating pediatric diarrhea in low- and middle-income countries. The pilot before-after feasibility trial will measure changes in antibiotic prescribing behavior following introduction of the tool, assessing acceptability, feasibility, and utility. The study targets informal healthcare providers who commonly serve as the first point of care for children under 5 in these settings and prescribe antibiotics at high rates despite rehydration being the accepted best practice for non-severe, non-cholera diarrhea.
Healthcare providers and researchers focused on pediatric care in LMICs should be aware that this study will generate evidence on whether mobile-based decision-support tools can meaningfully reduce inappropriate antibiotic prescribing in informal care settings. The results may inform future public health interventions targeting antimicrobial resistance in resource-limited environments.
Archived snapshot
Apr 20, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
The Utility and Feasibility of Accessible Diarrhea Etiology Prediction Tool (ADEPT) in an Informal Healthcare Setting
N/A NCT07538531 Kind: NA Apr 20, 2026
Abstract
Diarrheal disease remains a leading cause of morbidity and mortality for children under 5 globally. Accepted best practice for managing diarrhea in the absence of blood or suspicion of cholera is rehydration, however in resource poor areas antibiotics are still prescribed at high rates due to pressures such as financial incentives, caregiver expectations, and diagnostic uncertainty. Informal healthcare providers often serve as first point of care for pediatric diarrhea patients in low- and middle- income countries (LMICs) and commonly prescribe antibiotics for pediatric diarrhea at high frequencies.
In this pilot before-after feasibility trial informally trained healthcare providers will use a mobile phone-based application (Accessible Diarrhea Etiology Prediction Tool, ADEPT) which will allow for the exploration of the acceptability, feasibility, and utility of the tool, as well as ADEPTs ability to decrease inappropriate antibiotic prescribing practices.
Conditions: Diarrhea Infectious, Algorithms, Decision Support Systems, Clinical, Clinical Decision-making
Interventions: Diagnostic test: Accessible Diarrhea Etiology Prediction Tool (ADEPT)
Related changes
Get daily alerts for ClinicalTrials.gov Studies
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from NIH.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when ClinicalTrials.gov Studies publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.