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Web-Based Stroke Diagnostic Tests Validation Study (Observational, NCT07538076)

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Summary

The NIH registered observational study NCT07538076 to validate two web-based diagnostic tests — the Star Cancellation Test and Line Bisection Test — for assessing visuospatial neglect in hemiplegic stroke patients. The study will compare digital tablet-and-stylus versions of these tests against conventional paper-and-pencil assessments to evaluate diagnostic accuracy and clinical usability. Participants include stroke patients who will complete both conventional and digital versions of each test along with routine cognitive assessments.

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What changed

The NIH ClinicalTrials.gov registry added study NCT07538076, an observational validation study evaluating the clinical usability and diagnostic performance of web-based Star Cancellation and Line Bisection tests in stroke patients with visuospatial neglect. The study compares digital tablet-based versions of these conventional neuropsychological assessment tools against paper-and-pencil benchmarks, measuring parameters such as completion time, search speed, and search patterns.

Healthcare providers and clinical researchers conducting stroke rehabilitation or neuropsychological assessment should note this registry entry as background on emerging digital assessment methodologies. The study itself creates no new compliance obligations; however, institutions conducting similar comparative validation research should ensure their trials are registered on ClinicalTrials.gov in accordance with applicable federal requirements.

Archived snapshot

Apr 20, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Validation of Web-Based Star Cancellation and Line Bisection Tests in Hemiplegic Stroke

Observational NCT07538076 Kind: OBSERVATIONAL Apr 20, 2026

Abstract

The goal of this observational study is to evaluate the clinical usability and diagnostic performance of newly developed web-based Star Cancellation and Line Bisection tests in assessing visuospatial neglect in hemiplegic stroke patients. It will also compare these digital tests with conventional paper-and-pencil assessments.

The main questions it aims to answer are:

Can the web-based Star Cancellation and Line Bisection tests accurately distinguish between stroke patients with and without visuospatial neglect? Do digital test parameters (such as completion time, search speed, and search patterns) provide additional clinical information beyond conventional test scores? Researchers will compare the results of the web-based tests with standard paper-and-pencil tests to evaluate their diagnostic accuracy and clinical validity.

Participants will:

Complete conventional paper-and-pencil Star Cancellation and Line Bisection tests Perform web-based (digital) versions of the same tests using a tablet and stylus Undergo routine clinical and cognitive assessments as part of standard care Provide demographic and clinical information

Conditions: Stroke, Spatial Neglect, Spatial Neglect After Stroke

Interventions: Web-Based Star Cancellation Test, Web-Based Line Bisection Test

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Last updated

Classification

Agency
NIH
Published
April 20th, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Healthcare providers Clinical investigators
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Diagnostic test validation Stroke rehabilitation research
Geographic scope
United States US

Taxonomy

Primary area
Public Health
Operational domain
Clinical Operations
Topics
Medical Devices Healthcare

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