ACSS2 Inhibitors for Cancer, Alcoholism, Viral Infections
Summary
The USPTO has published a patent application (US20260085048A1) detailing novel ACSS2 inhibitors and their potential uses in treating cancer, alcoholism, and viral infections. The application was filed on September 8, 2025.
What changed
This document is a patent application (US20260085048A1) filed with the USPTO on September 8, 2025. It describes novel ACSS2 inhibitors and methods of use for treating various conditions including cancer, alcoholism, viral infections (such as CMV), alcoholic steatohepatitis (ASH), non-alcoholic steatohepatitis (NASH), obesity, anxiety, depression, PTSD, and inflammatory/autoimmune conditions.
As this is a patent application, it does not impose direct compliance obligations on regulated entities. However, it signifies potential future developments in drug discovery and therapeutic treatments. Companies involved in pharmaceutical research and development, particularly in oncology, infectious diseases, and metabolic disorders, should be aware of this filing as it may indicate new avenues for intellectual property and product development in these areas.
Archived snapshot
Mar 26, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
ACSS2 INHIBITORS AND METHODS OF USE THEREOF
Application US20260085048A1 Kind: A1 Mar 26, 2026
Inventors
Philippe NAKACHE, Omri EREZ, Simone BOTTI, Andreas GOUTOPOULOS, Harry FINCH
Abstract
The present invention relates to novel ACSS2 inhibitors having activity as anti-cancer therapy, treatment of alcoholism, and viral infection (e.g., CMV), composition and methods of preparation thereof, and uses thereof for treating viral infection, alcoholism, alcoholic steatohepatitis (ASH), non-alcoholic steatohepatitis (NASH), obesity/weight gain, anxiety, depression, post-traumatic stress disorder, inflammatory/autoimmune conditions and cancer, including metastatic cancer, advanced cancer, and dmg resistant cancer of various types.
CPC Classifications
C07D 231/22 A61K 31/4152 A61K 31/4155 A61K 31/4184 A61K 31/422 A61K 31/427 A61K 31/4439 A61K 31/454 A61K 31/497 A61K 31/506 A61K 45/06 A61P 3/00 A61P 25/00 A61P 29/00 A61P 31/12 A61P 35/00 A61P 37/02 C07D 231/20 C07D 231/26 C07D 233/70 C07D 401/04 C07D 401/10 C07D 401/12 C07D 401/14 C07D 403/04 C07D 403/10 C07D 403/12 C07D 405/04 C07D 405/10 C07D 405/12 C07D 405/14 C07D 409/04 C07D 409/12 C07D 413/10 C07D 413/12 C07D 413/14 C07D 417/12 C07F 5/025
Filing Date
2025-09-08
Application No.
19321644
Named provisions
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