177Lu peptide targets uPAR receptor for colorectal cancer treatment
Summary
USPTO granted patent US12589171B2 to TRT INNOVATIONS APS covering a 177-Lu labeled peptide for site-specific targeting of the Urokinase Plasminogen Activator Receptor (uPAR) for treatment of cancers with high uPAR expression, particularly colorectal cancer. The patent includes 9 claims and lists inventors Andreas Kjaer, Morten Persson, and Michael Ploug.
What changed
USPTO issued Patent No. US12589171B2 to TRT INNOVATIONS APS for a therapeutic composition comprising a 177-Lu labeled peptide targeting the uPAR receptor. The patent covers methods of treating colorectal cancer and other cancers associated with high uPAR expression by administering an effective amount of the labeled peptide. Filing date was January 7, 2021, with Application No. 17144067.
This is a routine patent grant conveying intellectual property rights. Pharmaceutical companies developing radiopharmaceuticals for oncology indications should review the patent claims to assess potential licensing needs or freedom-to-operate concerns. No compliance deadlines or regulatory actions are associated with this grant.
Archived snapshot
Mar 31, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
177-Lu labeled peptide for site-specific uPAR-targeting
Grant US12589171B2 Kind: B2 Mar 31, 2026
Assignee
TRT INNOVATIONS APS
Inventors
Andreas Kjaer, Morten Persson, Michael Ploug
Abstract
There is provided a 177-Lu labelled peptide for site-specific targeting of the Urokinase Plasminogen Activator Receptor (uPAR) thereby enabling treatment of a cancer disease associated with high uPAR expression; e.g. treatment of colorectal cancer by administering to a patient an effective amount of the 177-Lu labelled peptide.
CPC Classifications
A61K 51/00 A61K 51/08 A61K 51/088 A61K 2121/00 A61K 2123/00 C07K 16/2896 C07K 16/18 C12N 9/6465 C12N 9/72 A61P 35/00
Filing Date
2021-01-07
Application No.
17144067
Claims
9
Related changes
Get daily alerts for USPTO Patent Grants - Peptides (C07K)
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from USPTO.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when USPTO Patent Grants - Peptides (C07K) publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.