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177-Lu labeled peptide for site-specific uPAR-targeting

Grant US12589171B2 Kind: B2 Mar 31, 2026

Assignee

TRT INNOVATIONS APS

Inventors

Andreas Kjaer, Morten Persson, Michael Ploug

Abstract

There is provided a 177-Lu labelled peptide for site-specific targeting of the Urokinase Plasminogen Activator Receptor (uPAR) thereby enabling treatment of a cancer disease associated with high uPAR expression; e.g. treatment of colorectal cancer by administering to a patient an effective amount of the 177-Lu labelled peptide.

CPC Classifications

A61K 51/00 A61K 51/08 A61K 51/088 A61K 2121/00 A61K 2123/00 C07K 16/2896 C07K 16/18 C12N 9/6465 C12N 9/72 A61P 35/00

Filing Date

2021-01-07

Application No.

17144067

Claims

9