Changeflow GovPing Pharma & Life Sciences

Recent changes

GovPing tracks 141 sources for this role out of 2,348 total sources on GovPing, covering Guidance, Enforcement, Rule, Notice, and Consultation instruments. There were 722 changes in the last 7 days.

Health Canada issued a Type I recall for nitrous oxide chargers sold by DOODELZ, Gold Whip, and Whip-it! brands without market authorization, while the UK VMD called for a Class II recall of Zoetis's Scabigard Suspension for cutaneous administration. FDA classified Draeger's Atlan A350 anesthesia workstations as a Class I recall due to potential piston ventilator failure, and Morovan recalled approximately 4,000 units of Gel Nail Polish Remover for methylene chloride and chloroform contamination.

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Peptide Analogue for Treatment of Diabetes or Obesity

USPTO published patent application US20260097101A1 for a peptide analogue of pancreatic polypeptide (PP) intended for treating diabetes or obesity. Filed September 6, 2023 under application number 19110570, the invention also covers methods of treatment and use in manufacturing a medicament for these conditions.

Routine Notice Intellectual Property
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Methods for Treating Fatty Liver Disease (NASH) with Resmetirom

USPTO published patent application US20260097039A1 disclosing methods of treating fatty liver disease (non-alcoholic steatohepatitis/NASH) and improving liver fibrosis using resmetirom (2-(3,5-dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile) or its pharmaceutical salts. Inventors: Rebecca Taub and Dominic Labriola. Application filed December 10, 2025, and published April 9, 2026. This is a publication of a patent application, not a granted patent.

Routine Notice Intellectual Property
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Reboxetine Patent Application for Narcolepsy and Cataplexy Treatment

USPTO published patent application US20260097040A1 by Herriot Tabuteau covering methods of treating narcolepsy with cataplexy using reboxetine or esreboxetine. The application includes pharmaceutical compositions and instructions for use in treating the condition. Filing date was December 11, 2025, with publication on April 9, 2026.

Routine Notice Intellectual Property
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Compositions and Methods for Reprogramming Diseased Musculoskeletal Cells

USPTO published patent application US20260097131A1 titled 'Compositions and Methods for Reprogramming Diseased Musculoskeletal Cells.' The application (filed December 11, 2025) discloses compositions and methods for reprogramming diseased musculoskeletal cells both in vitro and in vivo using non-viral delivery of polynucleotides encoding transcription factors. The patent application is now publicly available.

Routine Notice Intellectual Property
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Mysimba Cardiovascular Risk and Annual Assessment Requirements

BfArM, in agreement with EMA, issued a Direct Healthcare Professional Communication regarding Mysimba (naltrexone/bupropion). The communication addresses long-term cardiovascular risks that have not been fully determined for patients treated beyond one year. New recommendations include discontinuation of treatment after one year if patients have not maintained at least 5% weight loss, and mandatory annual cardiovascular risk assessments for treatment continuation decisions.

Priority review Guidance Pharmaceuticals
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Eberth Antibiotics - Outdated Package Inserts Create Patient Safety Risk

Dr. Friedrich Eberth Arzneimittel GmbH issued a Direct Healthcare Professional Communication (DHPC) via BfArM alerting that certain batches of nine antibiotic and antifungal products have outdated package inserts, creating a potential patient safety risk. Affected products include multiple strengths of cefazolin, cefotaxime, ceftazidime, ceftriaxone, levofloxacin, moxifloxacin, and voriconazole. Healthcare professionals are advised to discard outdated package inserts and refer to the current package inserts provided with the communication.

Priority review Notice Pharmaceuticals
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Accupaque Visipaque Batch Risk Alert: Particle Contamination in Iohexol Iodixanol Solutions

GE Healthcare Buchler GmbH & Co. KG issued a Direct Healthcare Professional Communication (DHPC) alerting to a potential risk of particles in certain batches of Accupaque (iohexol) and Visipaque (iodixanol) solutions for injection filled into polypropylene bottles. The company instructs that only clear, particle-free solutions may be used per the Summary of Product Characteristics (SmPC), and this must be verified prior to administration.

Routine Notice Pharmaceuticals
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Phenhydan Injection: DHPC on Visual Particles, Filter Required

BfArM published an updated DHPC from Desitin Arzneimittel GmbH regarding Phenhydan solution for injection (phenytoin sodium), following particle contamination identified in batch 021950 during official sample analysis. The company clarified that a syringe filter with 0.2-0.45 µm pore size must be used when drawing up the solution, then removed before patient administration. This supersedes the November 2025 filter guidance which was corrected for accuracy.

Urgent Notice Pharmaceuticals
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Arixtra Recall: Needle Iron Particle Discoloration in Pre-filled Syringes

BfArM issued a Drug Safety Communication regarding Viatris Healthcare Limited's Arixtra (fondaparinux sodium) pre-filled syringes. Reports indicate brown discoloration and blockage in needles caused by oxidized iron particles. Affected batches must not be dispensed or administered if discoloration is observed.

Urgent Enforcement Pharmaceuticals
4d ago ClinicalTrials.gov
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Wearable Voice-Guided BBTi for Insomnia and Sleep Apnea (NCT07521319)

ClinicalTrials.gov registered interventional study (NCT07521319) evaluating a wearable voice-guided BBTi device for treating insomnia and sleep apnea. The single-center study is enrolling approximately 100 participants and will assess efficacy through sleep metrics over a 4-week intervention period.

Routine Notice Healthcare

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Filters

142 official sources tracked

Regs.gov: Food and Drug Administration

Updated 4m ago

USPTO Trademarks - Pharmaceuticals (Class 005)

Updated 11d ago

EPO Patent Bulletin - Therapeutics (A61P)

Updated 42m ago

USPTO Patent Applications - Pharma (A61K)

Updated 2d ago

USPTO Patent Applications - Biotech (C12N)

Updated 17h ago

ClinicalTrials.gov

Updated 2d ago

USPTO Patent Applications - Peptides (C07K)

Updated 2d ago

USPTO Patent Grants - Biotech (C12N)

Updated 36m ago

USPTO Patent Applications - Organic Chemistry (C07D)

Updated 4d ago

USPTO Patent Applications - Therapeutics (A61P)

Updated 2d ago

USPTO Patent Grants - Therapeutics (A61P)

Updated 19m ago

USPTO Patent Grants - Organic Chemistry (C07D)

Updated 12h ago

USPTO Patent Grants - Peptides (C07K)

Updated 7h ago

ANSM Drug & Device Safety Alerts

Updated 4m ago

FDA: Drug Recalls Class II

Updated 8d ago

FR: National Institutes of Health

Updated 5h ago

Health Canada Recalls & Safety Alerts

Updated 6m ago

Regs.gov: Centers for Medicare and Medicaid Services

Updated 22h ago

FR: Health and Human Services Department

Updated 5m ago

FR: Food and Drug Administration

Updated 5h ago

CPSC Product Recalls

Updated 13d ago

FR: Drug Enforcement Administration

Updated 12d ago

FDA Warning Letters

Updated 6d ago

MHRA Guidance & Safety

Updated 32m ago

FR: Centers for Disease Control and Prevention

Updated 1d ago

WHO News

Updated 3h ago

CMS Newsroom

Updated 5d ago

Regs.gov: Occupational Safety and Health Administration

Updated 20h ago

FR: Centers for Medicare & Medicaid Services

Updated 6m ago

DEA Press Releases

Updated 18d ago

DEA Public Safety Alerts

Updated 6d ago

HSA Singapore Announcements

Updated 22m ago

FDA Medical Device Recalls

Updated 1m ago

Regs.gov: Animal and Plant Health Inspection Service

Updated 5d ago

FDA Recalls & Safety Alerts

Updated 17h ago

Saudi SFDA News

Updated 21h ago

Regs.gov: Centers for Disease Control and Prevention

Updated 23h ago

Regs.gov: Food Safety and Inspection Service

Updated 11d ago

HHS OIG Reports & Publications

Updated 12d ago

FR: Health Resources and Services Administration

Updated 6d ago

FDA Press Releases

Updated 24h ago

ANSM France News

Updated 11m ago

WV Board of Pharmacy

Updated 10d ago

USP Compendial Notices

Updated 12d ago

NH Board of Pharmacy Actions

Updated 12d ago

FDA MedWatch Safety Alerts

Updated 21d ago

MS Board of Pharmacy News

Updated 27d ago

LA Board of Pharmacy News

Updated 27d ago

FDA AI-Enabled Medical Devices

Updated 23d ago

GA Board of Pharmacy Board Orders

Updated 22d ago

KS Board of Pharmacy Newsletters

Updated 20d ago

FDA Drug Recalls Class I

Updated 19d ago

FDA Debarment List

Updated 9d ago

EPO Patent Bulletin - Pharma (A61K)

Updated 9m ago

UK VMD

Updated 19m ago

PMPRB

Updated 25m ago

NICE Technology Appraisals

Updated 7d ago

ECHA News

Updated 14d ago

BfArM Drug Safety Communications

Updated 3d ago

FDA Guidance Documents

Updated 3h ago

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