Draft ADME-B Modeling for HHCB

EPA has published a draft ADME-B (Absorption, Distribution, Metabolism, Excretion - Bioaccumulation) modeling document for HHCB (Galaxolide), a synthetic fragrance compound. The document presents EPA's scientific methodology for modeling the bioaccumulation potential of this chemical substance.\n\nAffected parties including chemical manufacturers, fragrance producers, and downstream product manufacturers should review the draft modeling approach to understand how EPA may assess HHCB's environmental and health risks. Stakeholders may have opportunities to provide scientific input on the methodology.