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AG Rhea Joins Coalition Urging Federal Xylazine Controls

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Summary

V.I. Attorney General Gordon C. Rhea joined a bipartisan coalition of 40 attorneys general in urging Congress to pass the Combating Illicit Xylazine Act. The proposed federal legislation would classify xylazine—a non-opioid veterinary tranquilizer increasingly mixed with illicit opioids like fentanyl—as a controlled substance, enabling DEA tracking of manufacturing, preventing diversion, and mandating public reporting. The coalition argues this classification would give law enforcement critical tools to combat the rising threat of xylazine-linked overdose deaths.

Why this matters

This coalition letter signals growing state-level consensus that federal scheduling of xylazine is necessary to address its role in opioid overdose deaths. The involvement of 40 attorneys general across both parties indicates bipartisan support, increasing the likelihood of legislative action. Pharmaceutical companies manufacturing or distributing veterinary tranquilizers should prepare for potential DEA scheduling implications. Public health authorities may need to update overdose response protocols given xylazine's resistance to naloxone.

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What changed

Attorney General Rhea signed a coalition letter to House and Senate leadership urging immediate passage of the Combating Illicit Xylazine Act. The letter explains that xylazine, a veterinary tranquilizer not approved for human use, is increasingly mixed with fentanyl and does not respond to naloxone, making opioid overdoses more lethal. The proposed legislation would enable DEA to track manufacturing, prevent diversion, and mandate public reporting on xylazine development, distribution, and deaths.

Affected parties include pharmaceutical manufacturers of veterinary tranquilizers, law enforcement agencies, and public health authorities. If enacted, the legislation would create new controlled substance classification requirements for xylazine products and increase reporting obligations. Healthcare providers and harm reduction organizations should monitor legislative progress as the Senate Judiciary Committee has already advanced the bill with bipartisan support.

Archived snapshot

Apr 20, 2026

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doj-admin
April 1, 2026

April 7, 2026
U.S. Virgin Islands — On Monday, V.I. Attorney General Gordon C. Rhea on joined a bipartisan coalition of 40 other attorneys general in calling on Congress to pass the Combating Illicit Xylazine Act. The bipartisan legislation would classify the dangerous animal tranquilizer xylazine – which is often mixed with fentanyl and other opioids – as a federal controlled substance to better protect communities and reduce opioid overdose deaths. In a letter to House and Senate leadership, Attorney General Rhea and the coalition explain the dangers of illicit xylazine, which is causing an increasing number of opioid overdose deaths, and argue that federally classifying xylazine as a controlled substance is essential to helping law enforcement stop the spread of the drug.

“Illicit xylazine is a dangerous and growing threat, especially when mixed with opioids like fentanyl,” said Attorney General Gordon C. Rhea. “Classifying it as a controlled substance will give law enforcement critical tools to track, prevent, and combat its spread, help keep it from reaching our communities, and strengthen efforts to address the broader opioid crisis and save lives.”

Xylazine, widely known by its street name “tranq,” is a non-opioid veterinary tranquilizer used for large animals, including horses and deer, and is not approved for any human use. Xylazine is not an opioid and therefore does not respond to the overdose reversal drug naloxone, greatly increasing its lethality when mixed with opioids. In recent years, xylazine has been mixed with illicit opioids, most commonly fentanyl.

Attorney General Rhea and the coalition argue that the lack of information on xylazine’s development, distribution, and related deaths makes it difficult to track and stop the spread of the drug. The Combating Illicit Xylazine Act would classify xylazine as a controlled substance, would allow the Drug Enforcement Administration (DEA) to track the manufacturing of the drug, prevent diversion, and mandate public reporting. With more information on the development, distribution, and use of xylazine, law enforcement professionals would be better equipped to fight against this rising threat. Last week, the Senate Judiciary Committee advanced the legislation with strong bipartisan support. In their letter, the attorneys general urge Congress to immediately pass this legislation to help address the opioid epidemic and save lives.

The letter is led by the attorneys general of New York, Arkansas, Connecticut, and Tennessee. In addition to the U.S. Virgin Islands, joining the letter are the attorneys general of American Samoa, Arizona, California, Colorado, Delaware, District of Columbia, Georgia, Hawaii, Illinois, Indiana, Kansas, Kentucky, Louisiana, Maine, Michigan, Minnesota, Mississippi, Nevada, New Hampshire, New Jersey, New Mexico, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Utah, Vermont, Virginia, Washington, West Virginia, and Wyoming.

A copy of the letter is attached here.

FOR IMMEDIATE RELEASE
April 1, 2026

Sandra Goomansingh
Media Relations Director
(340) 774-5666 ext. 10105
Email: sandra.goomansingh@doj.vi.gov

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Last updated

Classification

Agency
USVI DOJ
Published
April 1st, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Law enforcement Public health authorities Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Controlled substance regulation Drug enforcement policy Public health advocacy
Geographic scope
United States US

Taxonomy

Primary area
Public Health
Operational domain
Compliance
Topics
Criminal Justice Controlled Substances

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