United States

PhRMA v. McCuskey - Pharmaceutical Pricing Regulation

The Fourth Circuit affirmed the district court's rulings in consolidated cases (Nos. 25-1054, 25-1055, 25-1056) challenging West Virginia's pharmaceutical pricing regulations. The pharmaceutical industry plaintiffs, led by PhRMA, challenged state authority to regulate drug pricing through the West Virginia Board of Pharmacy. Judge Richardson authored the majority opinion upholding the lower court; Judge Benjamin dissented.

Ocrelizumab subcutaneous study in pediatric RRMS patients

The National Library of Medicine registered clinical trial NCT07503340 on ClinicalTrials.gov, a study evaluating subcutaneous ocrelizumab in pediatric patients with relapsing-remitting multiple sclerosis (RRMS). The trial is sponsored by Genentech, Inc. and will assess the safety and pharmacokinetics of a subcutaneous formulation in patients aged 10 to under 18 years.

Women's heart health study on cardiovascular risk factors and interventions

The National Library of Medicine registered clinical trial NCT07502911 on ClinicalTrials.gov, a study examining cardiovascular risk factors and interventions for women's heart health. The trial involves evaluation of heart disease risk factors and potential therapeutic interventions in female participants.

Memantine rosuvastatin neuroprotection peripheral nerve disease trial

National Library of Medicine registered clinical trial NCT07504198 on ClinicalTrials.gov. The trial evaluates memantine and rosuvastatin for neuroprotection in peripheral nerve disease. This is a Phase 2 interventional study likely conducted at US clinical sites.

ClinicalTrials.gov NCT07502716 Study Registration

The National Library of Medicine published minimal content requirements for ClinicalTrials.gov study pages. Clinical trial sponsors and investigators must ensure their registrations include essential data elements such as study description, eligibility criteria, and outcome measures when registering trials on the federal database.

Crohn's Disease Exclusive Enteral Nutrition Clinical Trial

The National Library of Medicine registered a new clinical trial (NCT07504510) on ClinicalTrials.gov evaluating exclusive enteral nutrition therapy for Crohn's disease. The trial focuses on dietary intervention as a treatment modality for inflammatory bowel disease.

Clinical Trial Registration NCT07503730

The National Library of Medicine registered a new clinical trial (NCT07503730) on ClinicalTrials.gov. This is a routine registration of an interventional study. The record contains minimal information at this time, likely because the study is newly registered or is in early stages of setup.

Novo Nordisk Obesity Study Weight Loss Maintenance Drug NNC0487-0111

ClinicalTrials.gov registered a Phase 2 clinical trial (NCT07503210) conducted by Novo Nordisk evaluating the drug NNC0487-0111 for weight loss maintenance in obese patients. The study appears to assess how effectively participants maintain weight loss after initial treatment.

Phase I trial of BEN301 injection for autoimmune diseases using CD4+ CAR+ Foxp3+ cells

The National Library of Medicine registered a new Phase I clinical trial (NCT07502859) on ClinicalTrials.gov evaluating BEN301 injection for autoimmune diseases using CD4+ CAR+ Foxp3+ cells. The trial is categorized as Phase I, indicating early-stage safety and dosing evaluation. No compliance deadlines or penalties are associated with this clinical trial registration.

CFPB enforcement drops, mortgage compliance shifts to states

Goodwin law firm published its monthly mortgage market review documenting a continued decline in federal enforcement activity. The CFPB tracked only 12 publicly announced enforcement actions in 2025 (9 state, 3 federal), the second fewest in the decade-long tracking period and reflecting the lowest annual recovery. The analysis predicts increased state AG and private litigation activity as federal oversight diminishes.