Response to Comments on Bayer CropScience Maize Petition

APHIS issued a response document addressing comments received on Bayer CropScience's petition (Docket No. APHIS-2025-0021) for determination of nonregulated status for a genetically modified maize event. The agency summarized the substantive comments received, clarified its regulatory approach, and explained the scientific and policy basis for its evaluation. The response addresses issues related to environmental impact, food safety, and plant pest risk assessment.

Regulated entities, particularly developers of genetically modified agricultural products, should review the response to understand how APHIS interprets and applies its regulatory standards. While this document does not impose new compliance deadlines, it provides guidance on the agency's expectations for future petitions of a similar nature. Developers preparing petitions for determination of nonregulated status should ensure their submissions address the issues raised in this response.