NIH Publishes Revised Grants Policy Statement March 2026

NIH Guide Funding Opportunities

Published March 25th, 2026

Detected March 25th, 2026

Summary

The National Institutes of Health (NIH) has published the revised NIH Grants Policy Statement (NIHGPS), effective March 2026. This update incorporates new and modified requirements, clarifies policies, and implements changes in statutes, regulations, and policies since the April 2024 version.

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What changed

The National Institutes of Health (NIH) has issued a revised Grants Policy Statement (NIHGPS) effective March 2026. This updated policy statement serves as the standard terms and conditions for all NIH grants and cooperative agreements. It incorporates new and modified requirements, clarifies existing policies, and implements statutory, regulatory, and policy changes that have occurred since the April 2024 version, consolidating previous Guide Notices.

This revision impacts entities receiving NIH grants and cooperative agreements. While no specific compliance deadline is mentioned beyond the effective date of the policy statement itself, grant recipients should review the updated NIHGPS to ensure adherence to the latest terms and conditions. The NIH will continue to issue interim policy changes via Guide Notices and Federal Register Notices as needed. Inquiries can be directed to the NIH Office of Policy for Extramural Research Administration.

What to do next

Review the revised NIH Grants Policy Statement (March 2026) for updated terms and conditions.
Ensure internal policies and procedures align with the new NIHGPS requirements.

Source document (simplified)

Publication of the Revised NIH Grants Policy Statement (Rev. March 2026) for Fiscal Year 2026 Notice Number: NOT-OD-26-057

Key Dates

Release Date: March 25, 2026

Related Announcements

NOT-OD-24-115 – Publication of the Revised NIH Grants Policy Statement (Rev. April 2024) for Fiscal year 2024

Issued by

NATIONAL INSTITUTES OF HEALTH (NIH)

Purpose

The National Institutes of Health (NIH) announces publication of the updated NIH Grants Policy Statement (NIHGPS, rev. March 2026). The NIHGPS provides both up-to-date policy guidance that serves as NIH standard terms and conditions of award for all NIH grants and cooperative agreements, and extensive guidance to those who are interested in pursuing NIH grants.

This update incorporates new and modified requirements, clarifies certain policies, and implements changes in statutes, regulations, and policies that have been implemented through appropriate legal and/or policy processes since the previous version of the NIHGPS dated April 2024.

This version of the NIHGPS includes policies and requirements that have been published via Guide Notices in effect as of March 17, 2026. The updates published in this version of the NIHGPS consolidate all such Guide Notices and supersede the April 2024 version of the NIHGPS.

The current version of the NIHGPS, in both HTML and PDF formats, as well as previous versions of the NIHGPS and documents summarizing significant changes implemented with each revision, are available on the NIH Grants Policy website.

After the March 2026 NIHGPS is issued, NIH will continue to publish interim grants policy changes and/or clarifications through the issuance of NIH Guide Notices, available on the website, and Federal Register Notices as appropriate.