NIH Notice of Change to PAR-24-272 Award Information

Notice of Change to PAR-24-272 Clinical and Translational Science Award (UM1 Clinical Trial Optional) in Award Information Notice Number: NOT-TR-26-003

Key Dates

Release Date: March 04, 2026

Related Announcements

• September 04, 2024 - Clinical and Translational Science Award (UM1 Clinical Trial Optional). See NOFO PAR-24-272.

Issued by

National Center for Advancing Translational Sciences (NCATS)

Purpose

The purpose of this Notice is to inform potential applicants of the changes in the Award Information for PAR-24-272 Clinical and Translational Science Award (UM1 Clinical Trial Optional) for receipt dates of May 28, 2026 and September 28, 2026. Changes to the table in the Award Budget section of the NOFO include specifying the applicable receipt dates (May 28, 2026 and September 28, 2026), an update under the heading “Maximum Direct Cost Budget Requests for UM1” to indicate amounts listed are based on FY2020-FY2024 NIH funding data and which amounts are applicable to each corresponding Hub Tier. All changes are indicated in bold italics under the “Revised to Read” section of this Notice.

Section II. Award Information

Award Budget

Currently Reads:

The amount of funding that applicants can request depends on the amount of NIH funding they receive. After calculating the total amount of NIH funding received as described in Section IV. Application and Submission Information, 2. Content and Form of Application Submission, R&R Budget, applicants may request the following amounts:

| Size Eligibility Budget Tiers for NOFO Applicants
(NOFO receipt dates March 13, 2025, May 28, 2025, September 29, 2025) | Maximum Direct Cost Budget Requests for UM1 | |
| Hub Tier | 5-year average of the most current NIH Direct Cost (DC) Funding of the applicant institution, PLUS 5-year average of the most current NIH Direct Cost (DC) of any partner(s)*

(based on FY2019-FY2023 NIH Funding data) | UM1 |
| A | >$385,000,000 | $6,500,000 |
| C | $250,000,000 - $384,999,999 | $5,000,000 |
| T | $175,000,000 - $249,999,999 | $3,600,000 |
| G | <$174,999,999 | $2,600,000 |

Revised to Read:

Award Budget

The amount of funding that applicants can request depends on the amount of NIH funding they receive. After calculating the total amount of NIH funding received as described in Section IV. Application and Submission Information, 2. Content and Form of Application Submission, R&R Budget, applicants may request the following amounts:

| Size Eligibility Budget Tiers for NOFO Applicants
(NOFO receipt dates May 28, 2026, September 28, 2026) | Maximum Direct Cost Budget Requests for UM1 | |
| Hub Tier | 5-year average of the most current NIH Direct Cost (DC) Funding of the applicant institution, PLUS 5-year average of the most current NIH Direct Cost (DC) of any partner(s)*

(based on *FY2020-FY2024** NIH Funding data)* | UM1 |
| A | >$400,000,000 | $6,500,000 |
| C | $265,000,000 - $399,999,999 | $5,000,000 |
| T | $190,000,000 - $264,999,999 | $3,600,000 |
| G | <$189,999,999 | $2,600,000 |

All other aspects of the Notice of Funding Opportunity Announcement remain unchanged.

Inquiries

Please direct all inquiries to:

National Center for Advancing Translational Sciences (NCATS)
Telephone: 301-402-0264
Email: [email protected]

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