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Methods of Creating and Screening DNA-Encoded Libraries

The USPTO granted Patent US12606817B2 to X-Chem, Inc. (inventor: Richard W. Wagner) for methods of creating and screening DNA-encoded libraries for drug discovery applications. The patent contains 17 claims covering synthesis and screening methodologies that link functional moieties to initiator oligonucleotides for target binding identification. The filing date was June 19, 2020, with application number 16906626.