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HIP1 Inhibitor Patent US12605456B2, Utah Valley University

The USPTO granted Patent US12605456B2 to Utah Valley University on April 21, 2026, covering inhibitor compounds that target the Huntingtin Interacting Protein 1 (HIP1) enzyme. The patented composition comprises a tripeptide targeting sequence directing the compound to HIP1's active site, conjugated to a C-terminal electrophilic warhead configured to inactivate the enzyme. The patent contains 20 claims.