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Modified Cpf1 Guide RNA CRISPR Gene Editing Patent

The USPTO granted Patent US12606823B2 to inventor Kunwoo Lee covering a nucleic acid comprising a Cpf1 crRNA, a processing sequence 5′ of the Cpf1 crRNA, and an extension sequence 5′ of the processing sequence. The patent also covers compositions comprising the nucleic acid with a carrier and optionally Cpf1, as well as methods of genetically modifying eukaryotic target cells. The patent contains 29 claims and was filed on October 2, 2018.