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Plant-Based Diet CKD Feasibility Study, Changi General Hospital, Singapore

A two-year follow-up, single-center, open-label feasibility study will recruit outpatients from the Renal Medicine Clinic at Changi General Hospital, Singapore. Eligible patients with Stage 3 or 4 chronic kidney disease will be assigned to either a predominantly plant-based diet intervention (at least 50% protein from plant sources) with regular dietitian counselling, or a control group receiving standard CKD dietary advice. Six monthly assessments will measure eGFR, serum potassium, nutritional markers, and quality of life outcomes through questionnaires and food frequency records. The study aims to evaluate feasibility, safety regarding hyperkalaemia incidence, and potential benefit in terms of acidosis improvement in the Singaporean context.