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mTOR Inhibitor Compound for Neurodegenerative Diseases

The USPTO granted Patent US12605358B2 to ALIAD BIOPHARMA for a novel mTOR signaling pathway inhibitor compound. The invention was found to inhibit mTORC1 and mTORC2 activities, activate autophagy, and alleviate symptoms associated with Alzheimer's-type dementia in animal models. The patent covers pharmaceutical compositions for preventing or treating nervous system diseases including neurodegenerative diseases and mTORopathy.