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Bioactive Polypeptides for Plant Protection, Growth and Productivity

Favicon for changeflow.com USPTO Patent Grants - Peptides (C07K)
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Summary

USPTO granted Patent US12599649B2 to Spogen Biotech Inc. covering bioactive priming polypeptides for agricultural applications. The patent protects formulations containing 7 claims that enhance plant growth, yield, health, longevity, productivity, and vigor, while reducing abiotic stress and providing protection from disease, insects, and nematodes. The patent was filed on July 20, 2018.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

USPTO granted patent US12599649B2 to Spogen Biotech Inc. on April 14, 2026, covering bioactive priming polypeptides for use in agricultural formulations. The invention provides methods for applying these polypeptides exogenously to plant surfaces or endogenously to plant interiors to increase growth, yield, health, longevity, productivity, and vigor, decrease abiotic stress, protect from disease, insects, and nematodes, enhance innate immune response, and change plant architecture.

Agricultural biotechnology companies and crop protection firms should monitor this patent when developing similar peptide-based agricultural products to assess potential infringement issues or licensing needs.

What to do next

  1. Monitor for IP landscape changes in agricultural biotechnology

Archived snapshot

Apr 14, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Bioactive polypeptides for improvements in plant protection, growth and productivity

Grant US12599649B2 Kind: B2 Apr 14, 2026

Assignee

Spogen Biotech Inc.

Inventors

Brian Thompson, Michelle Leslie

Abstract

Bioactive priming polypeptides are provided that are useful when applied to plants in agricultural formulations. Methods of using the formulations containing the bioactive priming polypeptides are also provided which are applied exogenously to the surface of a plant or a plant cell membrane or endogenously to the interior of a plant or to a plant cell. The bioactive priming polypeptides when applied to a plant, a plant part, or a plant growth medium or a rhizosphere in an area surrounding the plant or the plant part increase growth, yield, health, longevity, productivity, and/or vigor of a plant or a plant part and/or decrease abiotic stress in the plant or the plant part and/or protect the plant or the plant part from disease, insects and/or nematodes, and/or increase the innate immune response of the plant or the plant part and/or change plant architecture.

CPC Classifications

A61K 38/164 A61K 38/16 A01N 63/50 C07K 14/32 C07K 14/325 C12P 21/02

Filing Date

2018-07-20

Application No.

16631581

Claims

7

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Last updated

Classification

Agency
USPTO
Published
April 14th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12599649B2

Who this affects

Applies to
Manufacturers Agricultural firms
Industry sector
1111 Crop Production
Activity scope
Patent issuance IP protection Agricultural biotechnology
Geographic scope
United States US

Taxonomy

Primary area
Agriculture
Operational domain
Legal
Topics
Intellectual Property

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