Changeflow GovPing Pharma & Drug Safety UniCel DxI 600 Total T4 Assay Recall
Urgent Enforcement Removed Final

UniCel DxI 600 Total T4 Assay Recall

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Filed March 10th, 2026
Detected March 20th, 2026
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Summary

Health Canada has issued a Type II recall for the UniCel DxI 600 Access Immunoassay System-Total T4 Assay due to a negative bias that can cause false low patient results. The recall affects specific lot numbers and poses a medium safety risk. Healthcare providers are advised to contact the manufacturer for further information.

What changed

Health Canada has issued a Type II recall for Beckman Coulter's UniCel DxI 600 Access Immunoassay System-Total T4 Assay, identified by lot numbers 538815, 539243, 538729, 538898, and 539107 (Model/Catalogue number 33805). The issue stems from Access Total T4 calibrator lots exhibiting a negative bias on DxI 600/800 instruments, leading to potential false low patient results. This performance issue presents a medium safety risk.

Healthcare providers using this system should be aware of the potential for inaccurate low thyroid hormone readings. While no specific action is mandated beyond contacting the manufacturer for information, awareness of this recall is critical for patient safety. The recall was published on March 10, 2026, with an original publication date of March 19, 2026.

What to do next

  1. Contact the manufacturer for additional information regarding the affected lots.

Source document (simplified)

Health product recall

UniCel DxI 600 Access Immunoassay System-Total T4 Assay

Brand(s)

BECKMAN COULTER, INC.

Last updated

2026-03-19

Summary

Product UniCel DxI 600 Access Immunoassay System-Total T4 Assay Issue Medical devices - Performance What to do Contact the manufacturer if you require additional information.

Audience Healthcare

Affected products

| Affected products | Lot or serial number | Model or catalogue number |
| --- | --- | --- |
| UniCel DxI 600 Access Immunoassay System-Total T4 Assay | 538815 | 33805 |
| UniCel DxI 600 Access Immunoassay System-Total T4 Assay | 539243 | 33805 |
| UniCel DxI 600 Access Immunoassay System-Total T4 Assay | 538729 | 33805 |
| UniCel DxI 600 Access Immunoassay System-Total T4 Assay | 538898 | 33805 |
| UniCel DxI 600 Access Immunoassay System-Total T4 Assay | 539107 | 33805 |

Issue

Access Total T4 calibrator lots (PN 33805) exhibit a negative bias on DxI 600/800 instruments, with slopes outside product specifications. In the worst-case scenario, there is a medium safety risk associated with this issue due to the potential to cause false low patient results.

Additional information

Details

Original published date:

2026-03-19

Alert / recall type Health product recall Category Health products - Medical devices - Chemistry Companies
| Beckman Coulter, Inc. |
| 250 S. Kraemer Blvd., Brea, California, United States, 92821 |
Published by Health Canada Audience Healthcare Recall class Type II Recall date

2026-03-10

Identification number RA-81777

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Named provisions

UniCel DxI 600 Access Immunoassay System-Total T4 Assay

Classification

Agency
Health Canada
Filed
March 10th, 2026
Instrument
Enforcement
Legal weight
Binding
Stage
Final
Change scope
Substantive
Document ID
RA-81777

Who this affects

Applies to
Healthcare providers
Industry sector
3345 Medical Device Manufacturing
Activity scope
Medical Device Performance
Geographic scope
Canada CA

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Medical Devices Product Safety

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