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Therapy Efficacy Method via Tissue Analysis, Arion Diagnostics

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Summary

USPTO granted Patent US12599349B2 to Arion Diagnostics, Inc. covering a method for determining therapeutic agent efficacy through non-invasive biological tissue characterization. The method involves measuring molecular structure of tissue at two time points and observing changes to determine efficacy. The patent includes 27 claims and covers therapeutic applications across multiple CPC classifications including oncology, immunology, and neurological disorders.

What changed

USPTO granted Patent US12599349B2 to Arion Diagnostics, Inc. for a method of determining therapeutic agent efficacy using non-invasive tissue analysis. The method involves measuring molecular structure of biological tissue at first and second time points and observing changes to assess whether a therapeutic agent is effective. Inventors are Alexander P. Lazarev, Delvin Tai Wai Yuk, and Pavel Lazarev.

For competitors and researchers in therapeutic development and diagnostics, this patent grants Arion Diagnostics exclusive rights to tissue-based efficacy determination methods, potentially restricting development of similar non-invasive therapy monitoring techniques without license.

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Apr 15, 2026

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← USPTO Patent Grants

Determining a therapy efficacy

Grant US12599349B2 Kind: B2 Apr 14, 2026

Assignee

Arion Diagnostics, Inc.

Inventors

Alexander P. Lazarev, Delvin Tai Wai Yuk, Pavel Lazarev

Abstract

The present disclosure relates to determining an efficacy of a therapeutic agent. A method for determining an efficacy of a therapeutic agent for a target disease can include measuring a molecular structure of a biological tissue of an animal at a first time and at a second time using a non-invasive biological tissue characterization technique. The method can further include observing a change of the molecular structure of the biological tissue between the first time and the second time, and determining the efficacy of the therapeutic agent based on the observed change in the molecular structure of the biological tissue. Before the first time, or between the first time and the second time, the animal received the therapeutic agent.

CPC Classifications

A61P 35/00 A61P 37/04 A61P 11/00 A61P 25/00 A61P 1/04 A61P 43/00 A61P 29/00 A61P 19/02 A61P 17/02 A61P 13/02 A61P 13/08 A61P 13/10 A61P 13/12 A61P 15/00 A61P 17/00 A61P 27/02 A61P 3/00 A61P 3/06 A61P 3/08 A61P 3/10 A61P 31/00 A61P 31/04 A61P 31/12 A61P 31/18 A61P 35/02 A61P 37/02 A61P 37/06 A61P 7/00 A61P 7/04 A61P 9/00 A61P 25/02 A61P 25/04 A61P 25/16 A61P 25/28 A61P 35/04 A61N 1/37 A61N 5/10 A61N 1/3629 A61B 5/0071 A61B 5/0075 A61B 5/4839 A61B 6/502 A61B 5/4848 A61B 5/7257 A61B 5/7275 A61B 5/7282

Filing Date

2023-04-10

Application No.

18298218

Claims

27

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Last updated

Classification

Agency
USPTO
Published
April 14th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12599349B2

Who this affects

Applies to
Healthcare providers Manufacturers Medical device makers
Industry sector
6211 Healthcare Providers
Activity scope
Patent examination IP licensing
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Medical Devices

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