Stem Cell Differentiation Method for Progenitor Cells and Organoids
Summary
The USPTO published patent application US20260098245A1 assigned to Koninklijke Nederlandse Akademie Van Wetenschappen (Royal Netherlands Academy of Arts and Sciences). The application, filed December 10, 2025, covers differentiation methods for progenitor cells including mammalian epithelial stem cells, differentiation media compositions for use in said methods, organoids and cells obtainable by said methods, and therapeutic uses thereof. Inventors are Johannes Carolus Clevers and Helmuth Gehart.
What changed
The USPTO published patent application US20260098245A1 covering differentiation methods for progenitor cells such as mammalian epithelial stem cells, differentiation media for use in said methods, and organoids and cells obtainable by said methods including therapeutic applications. The application lists 17 CPC classifications spanning cell culture methods (C12N 5/0672), therapeutic compositions (A61K 35/407), and screening methods (G01N 33/5088).
Affected parties in the biotechnology, pharmaceutical, and medical research sectors should monitor this patent application as it may affect research programs involving stem cell differentiation, organoid development, and related therapeutic applications. The broad claims covering differentiation media, cells, organoids, and therapeutic uses suggest potential licensing considerations for entities commercializing similar technologies.
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Apr 14, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Differentiation Method
Application US20260098245A1 Kind: A1 Apr 09, 2026
Assignee
Koninklijke Nederlandse Akademie Van Wetenschappen
Inventors
Johannes Carolus Clevers, Helmuth Gehart
Abstract
The invention relates to differentiation methods for progenitor cells, e.g. mammalian epithelial stem cells, differentiation media for use in said methods, organoids and cells obtainable by said methods and uses, including therapeutic uses, thereof.
CPC Classifications
C12N 5/0672 A61K 35/407 C12N 5/0671 G01N 33/5088 C12N 2501/01 C12N 2501/11 C12N 2501/119 C12N 2501/12 C12N 2501/155 C12N 2501/345 C12N 2501/39 C12N 2501/415 C12N 2501/42 C12N 2501/727 C12N 2501/805 C12N 2501/999 C12N 2506/14
Filing Date
2025-12-10
Application No.
19415547
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