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Spermidine and High Protein Composition for Autophagy Induction

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

European Patent Office published Patent EP3727419A1 by Société des Produits Nestlé S.A. covering a composition combining spermidine with high protein for induction of autophagy. The patent application was filed June 28, 2019 and designates all 35 EPO member states and extension states. Inventors include Gabriele Civiletto, Bernard Cuenoud, Jerome Feige, and Philipp Gut.

What changed

The EPO published European Patent Application EP3727419A1 for a novel combination of spermidine and high protein composition designed to induce autophagy. The patent protects compositions and methods for therapeutic use, classified under IPC A61K 38/01, A61K 38/17, A61K 31/132, and A61P 21/00. The application designates 35 contracting states covering the full EPO membership including all EU member states plus Switzerland, Norway, and other European countries.

Regulated entities in the pharmaceutical and nutritional supplement sectors should review this patent to assess freedom-to-operate implications for any competing spermidine and protein combination products targeting autophagy induction. No compliance actions or deadlines apply to this patent publication. Companies developing similar therapeutic compositions should consider patent mapping and potential licensing negotiations with Nestlé.

Source document (simplified)

← EPO Patent Bulletin

A COMBINATION OF SPERMIDINE AND HIGH PROTEIN COMPOSITION FOR INDUCTION OF AUTOPHAGY

Publication EP3727419A1 Kind: A1 Mar 25, 2026

Applicants

Société des Produits Nestlé S.A.

Inventors

CIVILETTO, Gabriele, CUENOUD, Bernard, FEIGE, Jerome, GUT, Philipp

IPC Classifications

A61K 38/01 20060101AFI20190628BHEP A61K 38/17 20060101ALI20190628BHEP A61K 31/132 20060101ALI20190628BHEP A61P 21/00 20060101ALI20190628BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP3727419A1

Who this affects

Applies to
Pharmaceutical companies Food manufacturers Consumers
Industry sector
3254 Pharmaceutical Manufacturing 3114 Food & Beverage Manufacturing
Activity scope
Patent Publication Pharmaceutical Composition Therapeutic Applications
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Consumer Protection Food Safety

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